John P. Cunha, DO, FACOEP
John P. Cunha, DO, is a U.S. board-certified Emergency Medicine Physician. Dr. Cunha's educational background includes a BS in Biology from Rutgers, the State University of New Jersey, and a DO from the Kansas City University of Medicine and Biosciences in Kansas City, MO. He completed residency training in Emergency Medicine at Newark Beth Israel Medical Center in Newark, New Jersey.
William C. Shiel Jr., MD, FACP, FACR
Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.
In this Article
- Melioidosis facts
- What is melioidosis? What causes melioidosis?
- Where does melioidosis occur?
- What are symptoms of melioidosis?
- How is melioidosis diagnosed?
- How is melioidosis treated?
- Can melioidosis be prevented?
- What is the prognosis for melioidosis?
How is melioidosis diagnosed?
The diagnosis of melioidosis is made with a microscopic evaluation of a blood, urine, sputum, or skin-lesion sample in the laboratory. A blood test is useful to detect early acute cases of melioidosis, but it can not exclude the illness if it is negative.
How is melioidosis treated?
The treatment of melioidosis involves antibiotics and depends on the location of the disease.
For patients with more mild illness, the CDC recommends antibiotics such as imipenem, penicillin, doxycycline, amoxicillin-clavulanic acid, ceftazidime, ticarcillin-clavulanic acid, ceftriaxone, and aztreonam. Patients who are more severely ill are given a combination of two of the above for three to six months.
Learn more about: ceftriaxone
With pulmonary involvement of melioidosis, if cultures remain positive for six months, surgical removal of the lung abscess with lobectomy is considered.
Can melioidosis be prevented?
In counties where melioidosis occurs, people with compromised immune systems (such as AIDS, cancer, those undergoing chemotherapy, etc.) should avoid contact with soil and contaminated water, especially in farm areas.
What is the prognosis for melioidosis?
Untreated, melioidosis is fatal. When treated with antibiotics, severe forms of the illness have an overall mortality rate of approximately 40%.
Medically reviewed by Robert Cox, MD; American Board of Internal Medicine with subspecialty in Infectious Disease
"Melloidosis: risk factors" Centers for Disease Control
U.S. Centers for Disease Control and Prevention
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