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Mellaril Patient Information Including Side Effects

Brand Names: Mellaril

Generic Name: thioridazine (Pronunciation: THYE oh RID a zeen)

What is thioridazine (Mellaril)?

Thioridazine is an anti-psychotic medication called a phenothiazine (FEEN-oh-THYE-a-zeen). It works by changing the actions of chemicals in your brain.

Thioridazine is used to treat psychotic disorders such as schizophrenia.

Thioridazine is usually given after other medications have been tried without successful treatment of schizophrenia.

Thioridazine may also be used for purposes not listed in this medication guide.

Thioridazine 10 mg-GG

round, red, imprinted with GG, 30

Thioridazine 10 mg-MUT

round, yellow, imprinted with MP12

Thioridazine 10 mg-MYL

round, orange, imprinted with M 54, 10

Thioridazine 100 mg-GG

round, red, imprinted with GG 34, 100

Thioridazine 100 mg-MUT

round, yellow, imprinted with MP 160

Thioridazine 100 mg-MYL

round, orange, imprinted with 100, M 61

Thioridazine 25 mg-GG

round, red, imprinted with GG 32, 25

Thioridazine 25 mg-MUT

round, yellow, imprinted with MP 14

Thioridazine 25 mg-MYL

round, orange, imprinted with M 58, 25

Thioridazine 50 mg-GG

round, red, imprinted with GG 33, 50

Thioridazine 50 mg-MUT

round, yellow, imprinted with MP 17

Thioridazine 50 mg-MYL

round, orange, imprinted with 50, M 59

What are the possible side effects of thioridazine (Mellaril)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using thioridazine and call your doctor at once if you have a serious side effect such as:

  • headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;
  • slow heart rate, weak pulse, fainting, slow breathing;
  • very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, feeling like you might pass out;
  • twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;
  • tremor (uncontrolled shaking), drooling, trouble swallowing, problems with balance or walking;
  • feeling restless, jittery, or agitated;
  • seizure (convulsions);
  • decreased night vision, tunnel vision, watery eyes, increased sensitivity to light;
  • pale skin, easy bruising or bleeding, fever, chills, flu symptoms, sores in your mouth and throat;
  • urinating less than usual or not at all; or
  • nausea and upper stomach pain, itching, and jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • drowsiness;
  • dry mouth, stuffy nose;
  • vomiting, constipation, diarrhea;
  • breast swelling or discharge;
  • changes in your menstrual periods;
  • weight gain, swelling in your hands or feet;
  • impotence, trouble having an orgasm;
  • increased or decreased interest in sex; or
  • mild itching or skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Mellaril (thioridazine hcl) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about thioridazine (Mellaril)?

You should not use this medication if you are allergic to thioridazine or other anti-psychotic drugs, or if you have untreated or uncontrolled high blood pressure (hypertension), very low blood pressure, a serious heart rhythm disorder, a history of Long QT syndrome, or if you are also using large amounts of alcohol or medicines that make you sleepy.

There are many other drugs that can cause serious or life threatening medical problems if you take them together with thioridazine. Tell your doctor about all other medicines you use.

Before you take thioridazine, tell your doctor if you have heart disease, high blood pressure, a heart rhythm disorder (especially slow heartbeats), low levels of potassium in your blood, past or present breast cancer, liver or kidney disease, a history of seizures, Parkinson's disease, enlarged prostate or urination problems, glaucoma, or if you have ever had a serious side effect while using thioridazine or a similar medication.

Thioridazine is not for use in psychotic conditions related to dementia. Thioridazine may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

Taking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. Do not start or stop taking thioridazine during pregnancy without your doctor's advice.

Drinking alcohol can increase certain side effects of thioridazine.

Stop using thioridazine and call your doctor at once if you have twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. These could be early signs of dangerous side effects.

Side Effects Centers

Mellaril - User Reviews

Mellaril User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Mellaril sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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