home > drugs a-z list > melquin-3 topical solution (hydroquinone 3% topical solution) drug center > melquin-3 topical solution (hydroquinone 3% topical solution) drug - clinical pharmacology

Topical application of hydroquinones produce a reversible depigmentation of the skin by the inhibition of the enzymatic oxidation of tyrosine to 3, 4-dihydroxyphenylalanine (DOPA) [Denton, C., et al, 1952 (1)] and supression of other melanocyte metabolic processes [Jimbow, K., et al, 1974 (2)]. Exposure to sunlight or ultraviolet light will cause repigmentation of the bleached areas [Parrish, J., et al, 1978 (3)].

Last reviewed on RxList: 1/20/2009
This monograph has been modified to include the generic and brand name in many instances.