"The US Food and Drug Administration (FDA) today approved asfotase alfa (Strensiq, Alexion Pharmaceuticals) as the first-ever therapy for patients who develop hypophosphatasia, a rare metabolic bone disorder, in childhood.
Menactra®, Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine, is indicated for active immunization to prevent invasive meningococcal disease caused by N meningitidis serogroups A, C, Y and W-135. Menactra is approved for use in individuals 9 months through 55 years of age. Menactra vaccine does not prevent N meningitides serogroup B disease.
Preparation For Administration
Menactra vaccine is a clear to slightly turbid solution. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. If any of these conditions exist, the vaccine should not be administered.
Withdraw the 0.5 mL dose of vaccine from the single-dose vial using a sterile needle and syringe.
Dose And Schedule
Menactra vaccine is administered as a 0.5 mL dose by intramuscular injection.
In children 9 through 23 months of age, Menactra is given as a 2-dose series three months apart.
Individuals 2 through 55 years of age receive a single dose.
Do not administer this product intravenously or subcutaneously.
DOSAGE AND ADMINISTRATION
The need for a booster dose of Menactra vaccine has not yet been determined.
Dosage Forms And Strengths
Menactra vaccine is a liquid solution supplied in 0.5 mL single-dose vials. [See DESCRIPTIONfor a complete listing of ingredients.]
Vial, 1 Dose (NDC 49281-589-58) supplied as a package of 5 vials (NDC 49281-589-05).
Storage And Handling
Store at 2° to 8°C (35° to 46°F). DO NOT FREEZE. Frozen/previously frozen product should not be used. Do not use after the expiration date.
Manufactured by: Sanofi Pasteur Inc., Swiftwater PA 18370 USAThis monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 12/28/2016
Additional Menactra Information
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