"Scientists at the National Institutes of Health report they have discovered in mouse studies that a small molecule released in the spinal cord triggers a process that is later experienced in the brain as the sensation of itch.
Mentax® (butenafine HCl cream), 1%, is indicated for the topical treatment of the following dermatologic infections: tinea (pityriasis) versicolor due to M. furfur (formerly P. orbiculare), interdigital tinea pedis (athlete's foot), tinea corporis (ringworm) and tinea cruris (jock itch) due to E. floccosum, T. mentagrophytes, T. rubrum, and T. tonsurans. Butenafine HCl cream was not studied in immunocompromised patients. (See DOSAGE AND ADMINISTRATION Section).
DOSAGE AND ADMINISTRATION
Patients with tinea (pityriasis) versicolor should apply Mentax® (butenafine) once daily for two weeks. In the treatment of interdigital tinea pedis, Mentax® (butenafine) should be applied twice daily for 7 days OR once daily for 4 weeks (NOTE: in separate clinical trials, the 7-day dosing regimen was less efficacious than the 4-week regimen (see Clinical Studies Section). While the clinical significance of this difference is unknown, these data should be carefully considered before selecting the dosage regiment for patients at risk for the development of bacterial cellulitis of the lower extremity associated with interdigital cracking/fissuring).
Patients with tinea corporis or tinea cruris should apply Mentax® (butenafine) once daily for two weeks.
Sufficient Mentax® (butenafine) Cream should be applied to cover affected areas and immediately surrounding skin of patients with tinea versicolor, interdigital tinea pedis, tinea corporis, and tinea cruris. If a patient shows no clinical improvement after the treatment period, the diagnosis and therapy should be reviewed.
Mentax® (butenafine HCl cream) Cream, 1%, is supplied in tubes in the following sizes:
15-gram tube (NDC 62794-151-02)
30-gram tube (NDC 62794-151-03)
STORE BETWEEN 5°C and 30°C (41° and 86°F).
Manufactured by: DPT Laboratories San Antonio, TX 78215. Distributed by: Bertek Pharmaceuticals Inc. Morgantown, WV 26505. June 6, 2001.
Last reviewed on RxList: 4/3/2009
This monograph has been modified to include the generic and brand name in many instances.
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