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Mephyton Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Mephyton (phytonadione) is used to treat vitamin K deficiency and to treat certain bleeding or blood clotting problems. It is a man-made form of vitamin K. Vitamin K usually has very few side effects. If you have any unusual effects from taking this medicine, tell your doctor.
To correct excessively prolonged prothrombin times caused by oral anticoagulant therapy the recommended initial adult dose of Mephyton is 2.5 to 10 mg or up to 25 mg. The recommended initial adult dose to treat hypoprothrombinemia due to other causes is 2.5 to 25 mg or more (rarely up to 50 mg). Mephyton may interact with warfarin, mineral oil, orlistat, cholestyramine, aspirin and other salicylates, non-steroidal anti-inflammatory drugs (NSAIDs), or antibiotics. Tell your doctor all medications you use. During pregnancy, Mephyton should be used only when prescribed. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.
Our Mephyton (phytonadione) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Mephyton in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
- fast or irregular heartbeats; or
- increased sweating.
Call your doctor at once if you have a serious side effect such as:
- feeling like you might pass out;
- blue colored lips; or
- trouble breathing.
Less serious side effects may include:
- flushing (warmth, redness, or tingly feeling);
- changes in your sense of taste;
- sweating; or
Read the entire detailed patient monograph for Mephyton (Phytonadione)
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Mephyton Overview - Patient Information: Side Effects
If your doctor has prescribed this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, tell your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Mephyton (Phytonadione)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Mephyton FDA Prescribing Information: Side Effects
Severe hypersensitivity reactions, including anaphylactoid reactions and deaths have been reported following parenteral administration. The majority of these reported events occurred following intravenous administration.
Transient "flushing sensations" and "peculiar" sensations of taste have been observed with parenteral phytonadione, as well as rare instances of dizziness, rapid and weak pulse, profuse sweating, brief hypotension, dyspnea, and cyanosis.
Hyperbilirubinemia has been observed in the newborn following administration of parenteral phytonadione. This has occurred rarely and primarily with doses above those recommended.
Read the entire FDA prescribing information for Mephyton (Phytonadione)
Additional Mephyton Information
Mephyton - User Reviews
Mephyton User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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