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meprobamate Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Meprobamate is used to relieve anxiety, nervousness, and tension associated with anxiety disorders. It acts on certain centers of the brain to help calm the nervous system. This medication is available in generic form. Common side effects include drowsiness, dizziness, headache, excitement, nausea, vomiting, and diarrhea.
The usual adult daily dosage of Meprobamate is 1200 mg to 1600 mg, in three or four divided doses. The usual daily dosage for children ages 6 to 12 years is 200 mg to 600 mg, in two or three divided doses. Meprobamate may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives, pain relievers, other anxiety medicines, and muscle relaxants. Tell your doctor all medications you use. Meprobamate is not recommended for use during the first 3 months of pregnancy due to the potential for harm to a fetus. During the last 6 months of pregnancy, it should be used only when prescribed. This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding. Withdrawal symptoms may occur if you suddenly stop taking this medication.
Our Meprobamate Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
meprobamate in Detail - Patient Information: Side Effects
If you experience any of the following serious side effects, stop taking meprobamate and seek emergency medical attention:
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, face, or tongue; or hives);
- fast or irregular heartbeats;
- abnormal behavior;
- a skin rash; or
- a sore throat.
Other, less serious side effects may be more likely to occur. Continue to take meprobamate and talk to your doctor if you experience
- drowsiness or dizziness,
- vomiting or diarrhea, or
- numbness or tingling.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for meprobamate (Meprobamate)
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
meprobamate Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: numbness/tingling/swelling of arms/legs.
Tell your doctor immediately if any of these rare but very serious side effects occur: fast/irregular heartbeat, fainting, signs of infection (such as fever, persistent sore throat), easy bruising/bleeding, change in the amount of urine, unusual tiredness.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for meprobamate (Meprobamate)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
meprobamate FDA Prescribing Information: Side Effects
Central Nervous System
Allergic or Idiosyncratic
Allergic or idiosyncratic reactions are usually seen within the period of the first to fourth dose in patients having had no previous contact with the drug. Milder reactions are characterized by an itchy, urticarial, or erythematous maculopapular rash which may be generalized or confined to the groin. Other reactions have included leukopenia, acute nonthrombocytopenic purpura, petechiae, ecchymoses, eosinophilia, peripheral edema, adenopathy, fever, fixed drug eruption with cross reaction to carisoprodol, and cross sensitivity between meprobamate/mebutamate and meprobamate/carbromal.
More severe hypersensitivity reactions, rarely reported, include hyperpyrexia, chills, angioneurotic edema, bronchospasm, oliguria and anuria. Also, anaphylaxis, erythema multiforme, exfoliative dermatitis, stomatitis, proctitis, Stevens-Johnson syndrome and bullous dermatitis, including one fatal case of the latter following administration of meprobamate in combination with prednisolone.
In case of allergic or idiosyncratic reactions to meprobamate, discontinue the drug and initiate appropriate symptomatic therapy, which may include epinephrine, antihistamines, and in severe cases, corticosteroids. In evaluating possible allergic reactions, also consider allergy to excipients.
Exacerbation of porphyric symptoms.
Read the entire FDA prescribing information for meprobamate (Meprobamate)
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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