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Mesnex

Urinary Tract Infection (UTI In Adults) »

Urinary tract infection (UTI) facts

  • Urinary tract infections (UTIs) are infections of the urethra, bladder, ureters, or the kidneys, which comprise the urinary tract.
  • E. coli bacteria cause the majority of UTIs, but many other bacteria, fungi, and parasites may also cause UTIs.
  • Females have a higher risk for UTIs than most males, probably because of their anatomy; other risk factors for UTIs include any condition that may impede urine flow (e.g., enlarged prostate, congenital urinary tract abnormalities, and inflammation). Patients with catheters or those who undergo urinary surgery and men with enlarged prostates are at higher risk for UTIs.
  • Symptoms and signs of UTI vary somewhat depending on sex, age, and the area of the urinary tract that is infected; some unique symptoms develop depending on the infecting agent.
  • UTIs are diagnosed usually by isolating and identifying the urinary pathogen from the patient; there a...

Read the Urinary Tract Infection (UTI In Adults) article »

Mesnex

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OVERDOSE

There is no known antidote for Mesnex (mesna) . Oral doses of 6.1 and 4.3 g/kg were lethal to mice and rats, respectively. These doses are approximately 15 and 22 times the maximum recommended human dose on a body surface area basis. Death was preceded by diarrhea, tremor, convulsions, dyspnea, and cyanosis.

CONTRAINDICATIONS

Mesnex (mesna) is contraindicated in patients known to be hypersensitive to mesna or other thiol compounds.

Last reviewed on RxList: 10/8/2008
This monograph has been modified to include the generic and brand name in many instances.

Additional Mesnex Information

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