Mestinon (Pyridostigmine) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

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Mestinon

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MESTINON®
(pyridostigmine bromide) Tablets, USP

SYRUP, TABLETS and TIMESPAN® TABLETS

DRUG DESCRIPTION

Mestinon (pyridostigmine bromide tablets, USP) is an orally active cholinesterase inhibitor. Chemically, pyridostigmine bromide is 3-hydroxy-1-methylpyridinium bromide dimethylcarbamate. Its structural formula is:

MESTINON (pyridostigmine bromide) Structural Formula Illustration

Mestinon (pyridostigmine) is available in the following forms: Syrup containing 60 mg pyridostigmine bromide per teaspoonful in a vehicle containing 5% alcohol, glycerin, lactic acid, sodium benzoate, sorbitol, sucrose, FD&C Red No. 40, FD&C Blue No. 1, flavors and water. Tablets containing 60 mg pyridostigmine bromide; each tablet also contains lactose, silicon dioxide and stearic acid. Timespan Tablets containing 180 mg pyridostigmine bromide; each tablet also contains carnauba wax, corn-derived proteins, magnesium stearate, silica gel and tribasic calcium phosphate.

What are the possible side effects of pyridostigmine (Mestinon, Mestinon Timespan)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

extreme muscle weakness;
severe vomiting or diarrhea;
vision problems; or
muscle cramps or twitching.

Other less serious side effects are more likely to occur, such as:

sweating or urinating more than...

Read All Potential Side Effects and See Pictures of Mestinon »

What are the precautions when taking pyridostigmine (Mestinon)?

Before taking pyridostigmine, tell your doctor or pharmacist if you are allergic to it; or to other anticholinesterase medications (e.g., neostigmine); or to bromides; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: stomach/intestinal blockage, urinary blockage.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: lung disease (e.g., asthma, chronic obstructive pulmonary disease-COPD), kidney disease, slow/irregular heartbeat.

Before having...

Read All Potential Precautions of Mestinon »

Last reviewed on RxList: 8/15/2008
This monograph has been modified to include the generic and brand name in many instances.