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Mestinon

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Mestinon

Mestinon

Mestinon Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Mestinon (pyridostigmine) is used to treat the symptoms of myasthenia gravis. It is also used in military personnel who have been exposed to nerve gas. It is a cholinesterase inhibitor. This medication is available in generic form. Common side effects include nausea, vomiting, diarrhea, abdominal cramps, increased saliva/mucus, decreased pupil size, increased urination, or increased sweating.

Mestinon is available in syrup, conventional tablets, and timespan (slow-release) tablets. Dose is adjusted for each patient. For syrup and conventional tablets, the average dose is ten 60 mg tablets or ten 5 mL teaspoonfuls daily. The dose for timespan tablets is one to three 180 mg tablets, once or twice daily. Mestinon may interact with atropine, belladonna, clidinium, dicyclomine, glycopyrrolate, hyoscyamine, mepenzolate, methantheline, methscopolamine, propantheline, scopolamine, antibiotics, or heart rhythm medications. Tell your doctor all medications you are taking. During pregnancy, Mestinon should be used only when prescribed. It is not known whether this medication passes into breast milk. Consult your doctor before breast-feeding.

Our Mestinon (pyridostigmine) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Mestinon in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using pyridostigmine and call your doctor at once if you have any of these serious side effects:

  • extreme muscle weakness, muscle twicthing;
  • slurred speech, vision problems;
  • severe vomiting or diarrhea;
  • cough with mucus;
  • confusion, anxiety, panic attacks;
  • seizure (convulsions); or
  • worsening or no improvement in your symptoms of myasthenia gravis.

Less serious side effects may include:

  • cold sweat, pale skin;
  • urinating more than usual;
  • watery eyes;
  • mild nausea, vomiting, or upset stomach;
  • warmth or tingly feeling; or
  • mild rash or itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Mestinon (Pyridostigmine) »

What is Patient Information Overview?

A concise overview of the drug for the patient or caregiver from First DataBank.

Mestinon Overview - Patient Information: Side Effects

SIDE EFFECTS: Nausea, vomiting, diarrhea, abdominal cramps, increased saliva/mucus, decreased pupil size, increased urination, or increased sweating may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: new or increased muscle cramps/weakness/twitching, shortness of breath, new or increased difficulty swallowing, slow heartbeat, dizziness, headache.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Read the entire patient information overview for Mestinon (Pyridostigmine)»

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Mestinon FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

The side effects of Mestinon (pyridostigmine) are most commonly related to overdosage and generally are of two varieties, muscarinic and nicotinic. Among those in the former group are nausea, vomiting, diarrhea, abdominal cramps, increased peristalsis, increased salivation, increased bronchial secretions, miosis and diaphoresis. Nicotinic side effects are comprised chiefly of muscle cramps, fasciculation and weakness. Muscarinic side effects can usually be counteracted by atropine, but for reasons shown in the preceding section the expedient is not without danger. As with any compound containing the bromide radical, a skin rash may be seen in an occasional patient. Such reactions usually subside promptly upon discontinuance of the medication.

Read the entire FDA prescribing information for Mestinon (Pyridostigmine) »

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Mestinon - User Reviews

Mestinon User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Mestinon sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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