METADATE ER Tablets (methylphenidate hydrochloride extended-release tablets, USP) are a mild central nervous system (CNS) stimulant. METADATE ER (methylphenidate hydrochloride tablet) is available as extended-release tablets of 10 and 20 mg for oral administration.

Methylphenidate hydrochloride is methyl a-phenyl-2-piperidineacetate hydrochloride, and its structural formula is:

Methylphenidate hydrochloride is a white, odorless, fine crystalline powder. Its solutions are acid to litmus. It is freely soluble in water and in methanol, soluble in alcohol, and slightly soluble in chloroform and in acetone. Its chemical formula is C₁₄H₁₉NO₂•HCl, and its molecular weight is 269.77.

Inactive Ingredients: Cetyl alcohol, ethylcellulose, anhydrous lactose and magnesium stearate.

Last reviewed on RxList: 5/26/2009
This monograph has been modified to include the generic and brand name in many instances.