"What are oral diabetes medications and how do they work?
Insulin is a hormone produced by cells in the pancreas called beta cells. Insulin helps the body use blood glucose (a type of sugar) for energy. People with type 2 diabetes "...
Metaglip Patient Information including If I Miss a Dose
In this Article
- What is glipizide and metformin (Metaglip)?
- What are the possible side effects of glipizide and metformin (Metaglip)?
- What is the most important information I should know about glipizide and metformin (Metaglip)?
- What should I discuss with my healthcare provider before taking glipizide and metformin (Metaglip)?
- How should I take glipizide and metformin (Metaglip)?
- What happens if I miss a dose (Metaglip)?
- What happens if I overdose (Metaglip)?
- What should I avoid while taking glipizide and metformin (Metaglip)?
- What other drugs will affect glipizide and metformin (Metaglip)?
- Where can I get more information?
What happens if I miss a dose (Metaglip)?
Take the missed dose as soon as you remember (be sure to take the medicine with food). Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Metaglip)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose may cause lactic acidosis. Get emergency medical help if you have any of these symptoms of lactic acidosis: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or uneven heart rate, dizziness, or feeling very weak or tired.
You may also have symptoms of severe hypoglycemia: extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).
What should I avoid while taking glipizide and metformin (Metaglip)?
Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.
What other drugs will affect glipizide and metformin (Metaglip)?
You may be more likely to have hyperglycemia (high blood sugar) if you take this medication with other drugs that can raise blood sugar, such as:
- diuretics (water pills);
- steroids (prednisone and others);
- heart or blood pressure medication (Cartia, Cardizem, Covera, Isoptin, Verelan, and others);
- niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others);
- phenothiazines (Compazine and others);
- thyroid medicine (Synthroid and others);
- birth control pills and other hormones;
- seizure medicines (Dilantin and others); and
- diet pills or medicines to treat asthma, colds or allergies.
You may be more likely to have hypoglycemia (low blood sugar) if you take other drugs that can lower blood sugar, such as:
- exenatide (Byetta);
- probenecid (Benemid);
- some nonsteroidal anti-inflammatory drugs (NSAIDs);
- aspirin or other salicylates (including Pepto-Bismol);
- sulfa drugs (Bactrim and others);
- a monoamine oxidase inhibitor (MAOI);
- beta-blockers (Tenormin and others); or
- other diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).
Tell your doctor about all other medicines you use, especially:
- furosemide (Lasix);
- nifedipine (Adalat, Procardia);
- cimetidine (Tagamet) or ranitidine (Zantac);
- amiloride (Midamor) or triamterene (Dyrenium);
- digoxin (Lanoxin);
- morphine (MS Contin, Kadian, Oramorph);
- procainamide (Procan, Pronestyl, Procanbid);
- quinidine (Quin-G);
- trimethoprim (Proloprim, Primsol, Bactrim, Cotrim, Septra);
- vancomycin (Vancocin, Lyphocin); or
- ketoconazole (Nizoral), itraconazole (Sporanox).
These lists are not complete and there are many other medicines that can increase or decrease the effects of glipizide and metformin on lowering your blood sugar. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about glipizide and metformin.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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