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(strontium-89 chloride) Injection
Metastron is a sterile, non-pyrogenic, aqueous solution of Strontium-89 Chloride for intravenous administration. The solution contains no preservative.
Each milliliter contains:
Strontium Chloride 10.9 -22.6
Water for Injection q.s. to 1 mL
The radioactive concentration is 37 MBq/mL, 1 mCi/mL, and the specific activity is 2.96-6.17 MBq/mg, 80-167 μCi/mg at calibration. The pH of the solution is 4 -7.5.
Strontium-89 decays by beta emission with a physical half-life of 50.5 days. The maximum beta energy is 1.463 MeV (100%). The maximum range of β-from Strontium-89 in tissue is approximately 8 mm.
Radioactive decay factors to be applied to the stated value for radioactive concentration at calibration, when calculating injection volumes at the time of administration, are given in Table 1.
Table 1: Decay of Strontium-89
|* Days before (-) or after (+) the calibration date stated on the vial.|
Last reviewed on RxList: 1/24/2014
This monograph has been modified to include the generic and brand name in many instances.
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