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Metastron (strontium-89) is a sterile, non-pyrogenic, aqueus solution of St rontium-89 Chloride for intravenous administration. The solution contains no preservative.

Each milliliter contains:

Strontium< Chloride 10.9 - 22.6 mg
Water for Injection q.s. to 1 mL

The radioactive concentration is 37 MBq/mL, 1 mCi/mL, and the specific activity is 2.96-6.17 MBq/mg, 80-167 μCi/mg at calibration. The pH of the solution is 4 - 7.5.

Physical Characteristics

Strontium-89 decays by beta emission with a physical half-life of 50.5 days. The maximum beta energy is 1.463 MeV (100%). The maximum range of β- from Strontium-89 in tissue is approximately 8 mm.

Radioactive decay factors to be applied to the stated value for radioactive concentration at calibration, when calculating injection volumes at the time of administration, are given in Table 1.

Table 1: Decay of Strontium-89

Last reviewed on RxList: 1/29/2009
This monograph has been modified to include the generic and brand name in many instances.