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Methadone Hydrochloride Patient Information including If I Miss a Dose
In this Article
- What is methadone (Methadone Hydrochloride)?
- What are the possible side effects of methadone (Methadone Hydrochloride)?
- What is the most important information I should know about methadone (Methadone Hydrochloride)?
- What should I discuss with my healthcare provider before using methadone (Methadone Hydrochloride)?
- How should I use methadone (Methadone Hydrochloride)?
- What happens if I miss a dose (Methadone Hydrochloride)?
- What happens if I overdose (Methadone Hydrochloride)?
- What should I avoid while using methadone (Methadone Hydrochloride)?
- What other drugs will affect methadone (Methadone Hydrochloride)?
- Where can I get more information?
What happens if I miss a dose (Methadone Hydrochloride)?
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
If you miss your doses for longer than 3 days in a row, call your doctor for instructions. You may need to restart methadone at a lower dose.
What happens if I overdose (Methadone Hydrochloride)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of methadone can be fatal, especially if you take it with alcohol or other narcotic medications.
Overdose symptoms may include extreme drowsiness, pinpoint pupils, confusion, cold and clammy skin, weak pulse, shallow breathing, fainting, or breathing that stops.
What should I avoid while using methadone (Methadone Hydrochloride)?
Do not drink alcohol. Methadone can increase the effects of alcohol, which could be dangerous. Check your food and medicine labels to be sure these products do not contain alcohol.
This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how methadone will affect you.
What other drugs will affect methadone (Methadone Hydrochloride)?
Do not use methadone with any other narcotic pain medications, sedatives, tranquilizers, sleeping pills, muscle relaxers, or other medicines that can make you sleepy or slow your breathing. Dangerous side effects may result.
Tell your doctor about all other medicines you use, especially:
- a diuretic (water pill);
- antibiotics such as azithromycin (Zithromax), ciprofloxacin (Cipro), clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), itraconazole (Sporanox), ketoconazole (Nizoral), metronidazole (Flagyl) or voriconazole (Vfend);
- heart or blood pressure medication such as diltiazem (Cardizem, Cartia, Dilacor, Tiazac) or verapamil (Calan, Covera, Isoptin, Verelan);
- HIV medicines such as abacavir (Ziagen), didanosine (Videx), efavirenz (Atripla, Sustiva), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Kaletra, Norvir), stavudine (Zerit), or zidovudine (Retrovir);
- an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate);
- other narcotic medications such as pentazocine (Talwin), nalbuphine (Nubain), buprenorphine (Subutex), or butorphanol (Stadol);
- rifampin (Rifadin, Rimactane, Rifater); or
- seizure medication such as phenobarbital (Solfoton) or phenytoin (Dilantin).
This list is not complete and there are many other drugs that can interact with Methadone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
Where can I get more information?
Your pharmacist can provide more information about methadone.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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Additional Methadone Hydrochloride Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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