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Methadone Hydrochloride

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Methadone Hydrochloride

Methadone Hydrochloride Patient Information Including Side Effects

Brand Names: Diskets, Dolophine, Methadose

Generic Name: methadone (Pronunciation: METH a done)

What is methadone (Methadone Hydrochloride)?

Methadone is an opioid pain medication. An opioid is sometimes called a narcotic. Methadone also reduces withdrawal symptoms in people addicted to heroin or other narcotic drugs without causing the "high" associated with the drug addiction.

Methadone is used as a pain reliever and as part of drug addiction detoxification and maintenance programs.

Methadone may also be used for purposes not listed in this medication guide.

Dolophine 5 mg-ROX

round, white, imprinted with 54 162

Methadone 10 mg-MAL

round, white, imprinted with METHADOSE 10

Methadone 10 mg-ROX

round, white, imprinted with 54 142

Methadone 5 mg-ROX

round, white, imprinted with 54 210

Methadose 5 mg

round, white, imprinted with METHADOSE 5

What are the possible side effects of methadone (Methadone Hydrochloride)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • shallow breathing;
  • hallucinations or confusion;
  • chest pain, dizziness, fainting, fast or pounding heartbeat; or
  • trouble breathing, feeling light-headed, or fainting.

Less serious side effects may include:

  • feeling anxious, nervous, or restless;
  • sleep problems (insomnia);
  • feeling weak or drowsy;
  • dry mouth, nausea, vomiting, diarrhea, constipation, loss of appetite; or
  • decreased sex drive, impotence, or difficulty having an orgasm.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the Methadone Hydrochloride (methadone) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about methadone (Methadone Hydrochloride)?

Taking methadone improperly will increase your risk of serious side effects or death. Even if you have used other narcotic medications, you may still have serious side effects from methadone. Follow all dosing instructions carefully.

Like other narcotic medicines, methadone can slow your breathing, even long after the pain-relieving effects of the medication wear off. Death may occur if breathing becomes too weak. Never use more methadone than your doctor has prescribed. Call your doctor if you think the medicine is not working.

Do not stop using methadone suddenly, or you could have unpleasant withdrawal symptoms. Call your doctor if you miss doses or forget to take this medication for longer than 3 days in a row.

Do not drink alcohol. Methadone can increase the effects of alcohol, which could be dangerous. Check your food and medicine labels to be sure these products do not contain alcohol.

This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how methadone will affect you.


Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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