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Methazolamide is indicated in the treatment of ocular conditions where lowering intraocular pressure is likely to be of therapeutic benefit, such as chronic open-angle glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma where lowering the intraocular pressure is desired before surgery.


The effective therapeutic dose administered varies from 50mg to 100mg 2 or 3 times daily. The drug may be used concomitantly with miotic and osmotic agents.


Methazolamide tablets, USP for oral administration are available as:

25mg: Round, white, unscored tablets debossed GG78 on one side and plain on the reverse side, and supplied as:

NDC 0781-1072-01 bottles of 100
NDC 0781-1072-10 bottles of 1000

50mg: Round, white, scored tablets debossed GG181 on one side and plain on the reverse side, and supplied as:

NDC 0781-1071-01 bottles of 100
NDC 0781-1071-10 bottles of 1000

Store at 20°-25°C (68°-77°F) (see USP Controlled Room Temperature).

Dispense in a tight, light-resistant container.

Rev. 01-2007. Sandoz Inc. Princeton, NJ 08540. FDA Rev date: n/a

Last reviewed on RxList: 9/2/2008
This monograph has been modified to include the generic and brand name in many instances.


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