"In a drug safety communication issued today, the US Food and Drug Administration (FDA) says it is aware of recent reports "questioning" the safety of prescription and over-the-counter (OTC) pain medicines when used during pregnancy, but that it l"...
(methylergonovine maleate) tablets, USP
Methergine is available in tablets for oral ingestion containing 0.2 mg methylergonovine maleate.
Active ingredient: Methylergonovine maleate, USP, 0.2 mg.
Inactive ingredients: acacia, corn starch, gelatin, lactose monohydrate, methylparaben, microcrystalline cellulose, povidone, propylparaben, stearic acid, and tartaric acid.
Chemically, methylergonovine maleate is designated as ergoline-8-carboxamide, 9, 10-didehydro-N- [1-(hydroxymethyl) propyl]-6-methyl-, [8β(S)]-, (Z)-2-butenedioate (1:1) (salt). Its structural formula is:
What are the possible side effects of methylergonovine (Methergine)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- pain, swelling, warmth, or redness under your skin;
- seizure (convulsions);
- feeling like you might pass out;
- pounding heartbeats or fluttering in your chest;
- slow heart rate, trouble breathing;
- blood in your urine;
- severe weakness, muscle cramps, confusion, slurred speech,...
What are the precautions when taking methylergonovine maleate (Methergine)?
Before taking methylergonovine, tell your doctor or pharmacist if you are allergic to it; or to similar ergot alkaloids (such as ergonovine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, high blood pressure, heart disease (such as venoatrial shunts, mitral valve stenosis, chest pain, recent heart attack), diabetes, high cholesterol, smoking/tobacco use, blood vessel disease (such as Raynaud's disease), complications during pregnancy (such as preeclampsia, eclampsia).
This drug may make you dizzy. Do not drive, use...
Last reviewed on RxList: 9/20/2016
This monograph has been modified to include the generic and brand name in many instances.
Additional Methergine Information
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