Methergine (Methylergonovine Maleate) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

Pill Identifier Search

May 26, 2012

« Previous
1
2
3
4
5
6
7
8
9
10
11
12
13
Next »

Methergine User Reviews >>

Methergine

Stages of Pregnancy Slideshow Pictures

Slideshow of Early Pregnancy Symptoms

Early Pregnancy Symptoms Quiz

font size

Methergine®
(methylergonovine maleate) Tablets, USP
(methylergonovine maleate) Injection, USP

DRUG DESCRIPTION

Methergine® (methylergonovine maleate) is a semi-synthetic ergot alkaloid used for the prevention and control of postpartum hemorrhage.

Methergine (methylergonovine maleate) is available in sterile ampuls of 1 mL, containing 0.2 mg methylergonovine maleate for intramuscular or intravenous injection and in tablets for oral ingestion containing 0.2 mg methylergonovine maleate.

Tablets

Active Ingredient: methylergonovine maleate, USP, 0.2 mg.

Inactive Ingredients: acacia, carnauba wax, D&C Red #7, FD&C Blue #1, gelatin special, lactose, maleic acid, mixed parabens, povidone, sodium benzoate, sodium hydroxide, starch, stearic acid, sucrose, talc, and titanium dioxide.

Ampuls, 1 mL, clear, colorless solution.

Active Ingredient: methylergonovine maleate, USP, 0.2 mg.

Inactive Ingredients: maleic acid, 0.10 mg; sodium chloride, 7.0 mg; water for injection, qs to 1 mL.

Chemically, methylergonovine maleate is designated as ergoline-8-carboxamide, 9,10-didehydro-N-[1-(hydroxymethyl)propyl]-6-methyl-, [8β(S)]-, (Z)-2-butenedioate (1:1) (salt).

Its structural formula is

Methergine (methylergonovine maleate) structural formula illustration

What are the possible side effects of methylergonovine (Methergine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

increased blood pressure (severe headache, blurred vision);
seizure (convulsions);
feeling light-headed, fainting;
pounding heartbeat;
chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;...

Read All Potential Side Effects and See Pictures of Methergine »

What are the precautions when taking methylergonovine maleate (Methergine)?

Before taking methylergonovine, tell your doctor or pharmacist if you are allergic to it; or to similar ergot alkaloids (such as ergonovine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, high blood pressure, heart disease (such as venoatrial shunts, mitral valve stenosis), blood vessel disease (such as Raynaud's disease), complications during pregnancy (such as preeclampsia, eclampsia).

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can...

Read All Potential Precautions of Methergine »

Last reviewed on RxList: 10/12/2010
This monograph has been modified to include the generic and brand name in many instances.