Methyclothiazide (Methyclothiazide Tablet 5 mg) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 9, 2012

Methyclothiazide

Diuretics »

What are diuretics and how do they work?

The amount of fluid (water) retained by the body is controlled primarily by the kidneys. This occurs due to the kidney's ability to control the retention and elimination of sodium and chloride, because the amounts of sodium, chloride, and water in the body are carefully balanced. Thus, if sodium and chloride are eliminated from the body, water also is eliminated. Conversely, if sodium and chloride are retained by the body, so is water.

The elimination of sodium, chloride, and water from the body is somewhat complex. In the kidneys, sodium, chloride, and other small molecules are filtered out of the blood and into the tubules of the kidney where urine is formed. Most of the sodium, chloride, and water are reabsorbed into the blood before the filtered fluid leaves the kidney in the form of urine. To make matters even more complex, there are different mechanisms that are active in different parts of the tu...

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Methyclothiazide

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Methyclothiazide
(methyclothiazide) Tablet 5 mg

DRUG DESCRIPTION

Methyclothiazide (methyclothiazide (methyclothiazide (methyclothiazide tablet 5 mg) tablet 5 mg) tablet 5 mg) , a diuretic-antihypertensive agent, is a member of the benzothiadiazine (thiazide) class of drugs. It is an analogue of hydrochlorothiazide and occurs as a white to practically white crystalline powder which is basically odorless. Methyclothiazide (methyclothiazide (methyclothiazide (methyclothiazide tablet 5 mg) tablet 5 mg) tablet 5 mg) is very slightly soluble in water and chloroform, and slightly soluble in alcohol. Chemically, methyclothiazide (methyclothiazide (methyclothiazide (methyclothiazide tablet 5 mg) tablet 5 mg) tablet 5 mg) is represented as 6-chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide. The structural formula is:

METHYCLOTHIAZIDE - methyclothiazide tablet Structural Formula Illustration

C₉H₁₁Cl₂N₃O₄S₂ M.W. 360.23

Each methyclothiazide tablet for oral administration contains 5 mg methyclothiazide (methyclothiazide (methyclothiazide (methyclothiazide tablet 5 mg) tablet 5 mg) tablet 5 mg) and the following inactive ingredients: colloidal silicon dioxide, magnesium stearate, microcrystalline cellulose, pregelatinized starch, sodium lauryl sulfate, sodium starch glycolate and FD&C Blue #1.

What are the precautions when taking methyclothiazide tablet 5 mg (Methyclothiazide)?

Before taking methyclothiazide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: severe kidney disease (inability to make urine).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, untreated salt/mineral imbalance (e.g., imbalance of sodium, potassium, calcium, magnesium), loss of too much body water (dehydration), high levels of fats in the blood (high...

Read All Potential Precautions of Methyclothiazide »

Last reviewed on RxList: 6/4/2009
This monograph has been modified to include the generic and brand name in many instances.