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Methyldopate Hcl

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Methyldopate Hcl

Methyldopate Hcl
(methyldopate hydrochloride) Injection, Solution

DRUG DESCRIPTION

Methyldopate HCl (methyldopate hydrochloride injection, solution) Injection, USP, is an antihypertensive agent for intravenous use. Sterile, nonpyrogenic.

Methyldopate hydrochloride [levo-3-(3,4-dihydroxyphenyl)-2-methylalanine, ethyl ester hydrochloride] is the ethyl ester of methyldopa, supplied as the hydrochloride salt with a molecular weight of 275.73. Methyldopate hydrochloride is more soluble and stable in solution than methyldopa and is the preferred form for intravenous use.

The molecular formula for Methyldopate hydrochloride is C12H17NO4·HCl and the structural formula is:

Methyldopate Hcl (methyldopate hydrochloride)  Structural Formula Illustration

Each mL contains:

Methyldopate Hydrochloride..................50 mg
Citric Acid (Anhydrous)..................5 mg
Edetate Disodium..................0.5 mg
Monothioglycerol..................2 mg
Water for Injection..................q.s. to 1 mL

Methylparaben 1.5 mg and Propylparaben 0.2 mg added as preservatives, Sodium Bisulfite 3.2 mg added as an antioxidant. pH adjusted with Sodium Hydroxide and/or Hydrochloric Acid.

Last reviewed on RxList: 8/11/2008
This monograph has been modified to include the generic and brand name in many instances.

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