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Methylene Blue Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Methylene Blue (methylene blue) injection is a form of hemoglobin, a substance in blood, used to treat methemoglobinemia. Methylene Blue oral is used to treat methemoglobinemia and urinary tract infections. Methylene Blue is also used as a dye or staining agent to make certain body fluids and tissues easier to view during surgery or on an x-ray or other diagnostic exam. Methylene Blue is available in generic form. Common side effects of Methylene Blue include abnormal urine or stool color. Less frequent side effects of Methylene Blue include mild bladder irritation, dizziness, headache, increased sweating, nausea, vomiting, diarrhea, upset stomach, frequent urination, or stomach cramps.
Methylene Blue is dosed 0.045 to 0.09 mL per pound of body weight. Methylene Blue may interact with acetazolamide, antacids, sodium bicarbonate, or diuretics (water pills). Tell your doctor all medications you are taking. Methylene blue may cause harm to a fetus, but the medication may sometimes be used during pregnancy. Your doctor will determine whether or not this medication is safe. Tell your doctor if you are pregnant. It is not known whether Methylene Blue passes into breast milk or if it could harm a nursing baby. Consult your doctor before breast-feeding.
Our Methylene Blue (methylene blue injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Methylene Blue in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- severe nausea, vomiting, or stomach pain;
- pain in your chest or behind your breast bone;
- pale or blue skin;
- high fever, fast or pounding heartbeats, trouble breathing; or
- confusion, feeling like you might pass out.
Less serious side effects may include:
- mild bladder irritation;
- mild nausea, vomiting, diarrhea, upset stomach;
- headache; or
- increased sweating.
Read the entire detailed patient monograph for Methylene Blue (Methylene Blue Injection)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Methylene Blue FDA Prescribing Information: Side Effects
Large intravenous doses of Methylene Blue (methylene blue injection) produce nausea, abdominal and precordial pain, dizziness, headache, profuse sweating, mental confusion and the formation of methemoglobin.
Use in Pregnancy
Safety for use in pregnancy has not been established. Use of Methylene Blue (methylene blue injection) in women of childbearing potential requires that anticipated benefits be weighed against possible hazards.
Read the entire FDA prescribing information for Methylene Blue (Methylene Blue Injection)
Additional Methylene Blue Information
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