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Methylene Blue

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Methylene Blue

Methylene Blue Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Methylene Blue (methylene blue) injection is used to treat methemoglobinemia. Methylene blue oral is used to treat methemoglobinemia and urinary tract infections. It is also used as a dye or staining agent to make certain body fluids and tissues easier to view during surgery or on an x-ray or other diagnostic exam. Methylene Blue is a form of hemoglobin, a substance in blood. This medication is available in generic form. Common side effects include abnormal urine or stool color. Less frequent side effects include mild bladder irritation, dizziness, headache, sweating, nausea/vomiting, diarrhea, frequent urination, or stomach cramps.

Methylene Blue is dosed 0.045 to 0.09 mL per pound of body weight. Methylene Blue may interact with acetazolamide, antacids, sodium bicarbonate, or diuretics (water pills). Tell your doctor all medications you are taking. Methylene blue may cause harm to a fetus, but the medication may sometimes be used during pregnancy. Your doctor will determine whether or not this medication is safe. Tell your doctor if you are pregnant. It is not known whether Methylene Blue passes into breast milk or if it could harm a nursing baby. Consult your doctor before breast-feeding.

Our Methylene Blue (methylene blue injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Methylene Blue in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • severe nausea, vomiting, or stomach pain;
  • pain in your chest or behind your breast bone;
  • pale or blue skin;
  • high fever, fast or pounding heartbeats, trouble breathing; or
  • confusion, feeling like you might pass out.

Less serious side effects may include:

  • mild bladder irritation;
  • mild nausea, vomiting, diarrhea, upset stomach;
  • dizziness;
  • headache; or
  • increased sweating.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Methylene Blue (Methylene Blue Injection) »

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Methylene Blue FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

Large intravenous doses of Methylene Blue (methylene blue injection) produce nausea, abdominal and precordial pain, dizziness, headache, profuse sweating, mental confusion and the formation of methemoglobin.

Use in Pregnancy

Safety for use in pregnancy has not been established. Use of Methylene Blue (methylene blue injection) in women of childbearing potential requires that anticipated benefits be weighed against possible hazards.

Read the entire FDA prescribing information for Methylene Blue (Methylene Blue Injection) »

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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