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Metopirone

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Metopirone

Metopirone®
(metyrapone USP) Capsules

Diagnostic Test of Pituitary Adrenocorticotropic Function

DRUG DESCRIPTION

Metopirone, metyrapone USP, is an inhibitor of endogenous adrenal corticosteroid synthesis, available as 250-mg capsules for oral administration. Its chemical name is 2-methyl-l, 2-di-3-pyridyl-l-propanone, and its structural formula is

Metopirone® 
   (metyrapone) Structural Formula Illustration

Metyrapone USP is a white to light amber, fine, crystalline powder, having a characteristic odor. It is sparingly soluble in water, and soluble in methanol and in chloroform. It forms water-soluble salts with acids. Its molecular weight is 226.28.

Inactive Ingredients. Polyethylene glycol, glycerine, gelatin, sodium ethyl hydroxybenzoate, sodium propyl hydroxybenzoate, ethyl vanillin, 4-methoxyacetophenone, titanium dioxide, brown ink.

What are the precautions when taking metyrapone (Metopirone)?

Before taking metyrapone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: decreased adrenal gland function (primary adrenal insufficiency), thyroid problems.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. A...

Read All Potential Precautions of Metopirone »

Last reviewed on RxList: 12/14/2010
This monograph has been modified to include the generic and brand name in many instances.

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Metopirone - User Reviews

Metopirone User Reviews

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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