"The US Food and Drug Administration (FDA) today approved asfotase alfa (Strensiq, Alexion Pharmaceuticals) as the first-ever therapy for patients who develop hypophosphatasia, a rare metabolic bone disorder, in childhood.
Cardiovascular System: Hypotension
Gastrointestinal System: Nausea, vomiting, abdominal discomfort or pain.
Central Nervous System: Headache, dizziness, sedation.
Dermatologic System: Allergic rash.
Hematologic System: Rarely, decreased white blood cell count or bone marrow depression.
Read the Metopirone (metyrapone) Side Effects Center for a complete guide to possible side effects
Drugs affecting pituitary or adrenocortical function, including all corticosteroid therapy, must be discontinued prior to and during testing with Metopirone (metyrapone) .
The metabolism of Metopirone (metyrapone) is accelerated by phenytoin; therefore, results of the test may be inaccurate in patients taking phenytoin within two weeks before. A subnormal response may occur in patients on estrogen therapy.
Metopirone (metyrapone) inhibits the glucuronidation of acetaminophen and could possibly potentiate acetaminophen toxicity.
Read the Metopirone Drug Interactions Center for a complete guide to possible interactions
Last reviewed on RxList: 12/14/2010
Additional Metopirone Information
- Metopirone Drug Interactions Center: metyrapone oral
- Metopirone Side Effects Center
- Metopirone Overview including Precautions
- Metopirone FDA Approved Prescribing Information including Dosage
Metopirone - User Reviews
Metopirone User Reviews
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