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Metopirone Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Metopirone (metyrapone) is a diagnostic drug for testing hypothalamic-pituitary ACTH function. Common side effects of Metopirone include nausea, vomiting, stomach upset or pain, headache, dizziness, drowsiness, or tiredness.
Metopirone is usually administered as a single-dose test. Adults and children are given the same 30 mg/kg dose (maximum 3 g Metopirone) at midnight with yogurt or milk. A blood sample is taken early the following morning. Metopirone may interact with acetaminophen, cyproheptadine, estrogens, and hydantoins (such as phenytoin). Do not drive, use machinery, or do any activity that requires alertness or clear vision while taking Metopirone. Avoid alcoholic beverages. Metopirone should be used during pregnancy only if clearly needed. It is not known if Metopirone passes into breast milk. Consult your doctor before breastfeeding.
Our Metopirone Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Metopirone Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Metopirone (Metyrapone)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Metopirone FDA Prescribing Information: Side Effects
Cardiovascular System: Hypotension
Gastrointestinal System: Nausea, vomiting, abdominal discomfort or pain.
Central Nervous System: Headache, dizziness, sedation.
Dermatologic System: Allergic rash.
Hematologic System: Rarely, decreased white blood cell count or bone marrow depression.
Read the entire FDA prescribing information for Metopirone (Metyrapone)
Additional Metopirone Information
- Metopirone Drug Interactions Center: metyrapone oral
- Metopirone Side Effects Center
- Metopirone Overview including Precautions
- Metopirone FDA Approved Prescribing Information including Dosage
Metopirone - User Reviews
Metopirone User Reviews
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