May 23, 2017
Recommended Topic Related To:


"The U.S. Food and Drug Administration today approved the first generic version of Nexium (esomeprazole magnesium delayed-release capsules) to treat gastroesophageal reflux disease (GERD) in adults and children ages 1 and older. Esomeprazole"...


Metozolv ODT

Metozolv ODT Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking metoclopramide (Metozolv ODT)?

You should not take this medication if you are allergic to metoclopramide, or if you have:

  • bleeding or blockage in your stomach or intestines;
  • a perforation (hole) in your stomach or intestines;
  • epilepsy or other seizure disorder; or
  • an adrenal gland tumor (pheochromocytoma).

To make sure you can safely take metoclopramide, tell your doctor if you have any of these other conditions:

  • kidney disease;
  • liver disease (especially cirrhosis);
  • congestive heart failure, a heart rhythm disorder;
  • high blood pressure;
  • breast cancer;
  • Parkinson's disease;
  • diabetes (your insulin dose may need adjusting); or
  • depression or mental illness.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Metoclopramide can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

The metoclopramide orally disintegrating tablet (ODT) may contain phenylalanine. Talk to your doctor before using this form of metoclopramide if you have phenylketonuria (PKU).

Metoclopramide should not be given to a child.

How should I take metoclopramide (Metozolv ODT)?

Take exactly as prescribed by your doctor. Metoclopramide is usually taken for only 4 to 12 weeks. Follow the directions on your prescription label.

NEVER TAKE METOCLOPRAMIDE IN LARGER AMOUNTS THAN RECOMMENDED, OR FOR LONGER THAN 12 WEEKS. High doses or long-term use of metoclopramide can cause a serious movement disorder that may not be reversible. Symptoms of this disorder include uncontrollable muscle movements of your lips, tongue, eyes, face, arms, or legs. The longer you take metoclopramide, the more likely you are to develop a serious movement disorder. The risk of this side effect is higher in women, diabetics, and older adults.

Take metoclopramide 30 minutes before eating. Metoclopramide is usually taken before meals and at bedtime. Your doctor may want you to take the medication as needed only with meals that usually cause heartburn. Follow your doctor's instructions.

Measure the liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

To take metoclopramide orally disintegrating tablet (ODT):

  • Keep the tablet in its bottle or blister pack until you are ready to take the medicine. Make sure your hands are dry before handling a tablet. If the tablet breaks or melts in your hand, throw it away and use a new tablet.
  • Place the tablet on your tongue. It will begin to melt right away. Do not swallow the tablet whole. Allow it to melt in your mouth without chewing.
  • Swallow several times as the tablet melt. You do not need to drink liquid to help the tablet melt.

Do not take two different forms of metoclopramide (such as tablets and oral syrup) at the same time.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

After you stop taking metoclopramide, you may have unpleasant withdrawal symptoms such as headache, dizziness, or nervousness. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication.

Side Effects Centers

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

GI Disorders

Get the latest treatment options.