home > drugs a-z list > metrodin (urofollitropin for injection) drug center > metrodin (urofollitropin for injection) drug - overdosage and contraindications

Aside from possible ovarian hyperstimulation and multiple gestations (see WARNINGS), little is known concerning the consequences of acute overdosage with Metrodin® (urofollitropin for injection) .

Metrodin® (urofollitropin for injection) is contraindicated in women who exhibit:

1. High levels of FSH indicating primary ovarian failure.

2. Uncontrolled thyroid or adrenal dysfunction.

3. An organic intracranial lesion such as a pituitary tumor.

4. The presence of any cause of infertility other than anovulation, as stated in the Indications unless they are candidates for Assisted Reproductive Technologies.

5. Abnormal bleeding of undetermined origin (see Selection of Patients).

6. Ovarian cysts or enlargement of undetermined origin.

7. Prior hypersensitivity to urofollitropin.

Metrodin® (urofollitropin for injection) is also contraindicated in women who are pregnant and may cause fetal harm when administered to a pregnant woman. There are limited human data on the effects of Metrodin® (urofollitropin for injection) when administered during pregnancy.

Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.