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Miacalcin

Hypercalcemia Introduction

Calcium is a mineral that is important in the regulation and processes of many body functions including bone formation, hormone release, muscle contraction, and nerve and brain function. Hypercalcemia is the term that refers to elevated levels of calcium in the bloodstream.

Regulation of Calcium

Calcium levels are tightly regulated in the body. Calcium regulation is primarily controlled by parathyroid hormone (PTH), vitamin D, and calcitonin.

  • Parathyroid hormone is a hormone produced by the parathyroid glands, which are four small glands that surround the thyroid and are found in the anterior part of the lower neck.
  • Vitamin D is obtained through a process that begins with sun exposure to the skin, the process then continues in the liver and kidneys. Vitamin D can also be found in foods such as eggs and dairy products.
  • Calcitonin is produc...

Miacalcin

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OVERDOSE

A dose of l000 I.U. subcutaneously may produce nausea and vomiting as the only adverse effects. Doses of 32 units per kg per day for 1-2 days demonstrate no other adverse effects.

Data on chronic high-dose administration are insufficient to judge toxicity.

CONTRAINDICATIONS

Clinical allergy to synthetic calcitonin-salmon.

Last reviewed on RxList: 5/2/2012
This monograph has been modified to include the generic and brand name in many instances.

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