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Microzide Side Effects Center
Medical Editor: Eni Williams, PharmD, PhD
Microzide (hydrochlorothiazide) is a medication that belongs to the drug class, diuretic. It is available as a generic drug, and is prescribed for lowering blood pressure (hypertension) and accumulation of fluid (edema). Common side effects of Microzide include weakness, low blood pressure, light sensitivity, impotence, nausea, abdominal pain, electrolyte disturbances, pancreatitis, jaundice, anaphylaxis, and rashes.
Microzide dose ranges from 12.5 to 100 mg/day depending on the condition that is being treated. Drug interactions include Lithobid (lithium), Motrin (ibuprofen), Lanoxin (digoxin) and Questran (cholestyramine). There are no adequate studies of Microzide in pregnant women and it is excreted in breast milk.
Our Microzide Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Microzide in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have a serious side effect such as:
- eye pain, vision problems;
- dry mouth, thirst, nausea, vomiting;
- feeling weak, drowsy, restless, or light-headed;
- fast or uneven heartbeat;
- muscle pain or weakness;
- numbness or tingly feeling;
- a red, blistering, peeling skin rash; or
- nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
- mild stomach pain;
- constipation; or
- blurred vision.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Microzide (Hydrochlorothiazide Capsule) »
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Microzide Overview - Patient Information: Side Effects
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
This medication may cause a serious loss of body water (dehydration) and salt/minerals. Tell your doctor right away if any of these unlikely but serious side effects occur: muscle cramps/weakness, slow/fast/irregular heartbeat, unusual decreased urination, unusual dry mouth/thirst, decrease in vision, eye pain.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Microzide (Hydrochlorothiazide Capsule)»
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Microzide FDA Prescribing Information: Side Effects
The adverse reactions associated with hydrochlorothiazide have been shown to be dose related. In controlled clinical trials, the adverse events reported with doses of 12.5 mg hydrochlorothiazide once daily were comparable to placebo. The following adverse reactions have been reported for doses of hydrochlorothiazide 25 mg and greater and, within each category, are listed in the order of decreasing severity.
Body as a whole: Weakness.
Hypersensitivity: Anaphylactic reactions, necrotizing angiitis (vasculitis and cutaneous vasculitis), respiratory distress including pneumonitis and pulmonary edema, photosensitivity, fever, urticaria, rash, purpura.
Musculoskeletal: Muscle spasm.
Renal: Renal failure, renal dysfunction, interstitial nephritis (see WARNINGS).
Whenever adverse reactions are moderate or severe, thiazide dosage should be reduced or therapy withdrawn.
Read the entire FDA prescribing information for Microzide (Hydrochlorothiazide Capsule) »
Additional Microzide Information
Microzide - User Reviews
Microzide User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Get tips on handling your hypertension.