Midamor
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Midamor
Please Note: This Brand Name drug is no longer available in the US.(Generic versions may still be available.)
Midamor Side Effects Center
Medical Editor: Charles Patrick Davis, MD, PhD
Midamor (amiloride HCl) is an antikaliuretic diuretic agent. This drug is no longer available in the US (generic versions may still be available). Miamor is indicated as adjunctive treatment with thiazide diuretics or other kaliuretic-diuretic agents in congestive heart failure or hypertension. Some side effects include but are not limited to: numbness or tingly feeling, muscle pain or weakness, slow, fast, or uneven heartbeat.
Midamor was available in 5 mg tablets. Midamor should be administered with food. One 5 mg tablet daily, should be added to the usual antihypertensive or diuretic dosage of a kaliuretic diuretic. The dosage may be increased to 10 mg per day if necessary. Serious side effects include hyperkalemia. There are, no adequate and well-controlled studies in pregnant women or pediatric patients. The drug should be used during pregnancy only if clearly needed. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Our Miamor (amiloride HCl) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Midamor in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these serious side effects:
- numbness or tingly feeling;
- muscle pain or weakness;
- slow, fast, or uneven heartbeat;
- feeling drowsy, restless, or light-headed;
- urinating less than usual or not at all;
- dry mouth, increased thirst, tiredness, nausea, vomiting;
- shallow breathing;
- tremors, confusion; or
- nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
- headache;
- mild nausea, loss of appetite;
- gas, stomach pain; or
- skin rash.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Midamor (Amiloride) »
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Midamor Overview - Patient Information: Side Effects
Headache, dizziness, nausea, vomiting, loss of appetite, stomach/abdominal pain, gas, or diarrhea may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
When given with other diuretics, amiloride may cause a loss of too much body water (dehydration) and salt/minerals. Tell your doctor immediately if you have any of these unlikely but serious symptoms of dehydration or mineral loss: very dry mouth, extreme thirst, muscle cramps, weakness, fast heartbeat, severe dizziness, confusion, unusual decrease in the amount of urine, fainting, seizures.
Tell your doctor immediately if any of these rare but serious side effects occur: yellowing eyes/skin, dark urine, persistent nausea/vomiting.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Midamor (Amiloride)»
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Midamor FDA Prescribing Information: Side Effects
(Adverse Reactions)
SIDE EFFECTS
MIDAMOR (amiloride) is usually well tolerated and except for hyperkalemia (serum potassium levels greater than 5.5 mEq per liter † see BOXED WARNING), significant adverse effects have been reported infrequently. Minor adverse reactions were reported relatively frequently (about 20%) but the relationship of many of the reports to amiloride HCl is uncertain and the overall frequency was similar in hydrochlorothiazide treated groups. Nausea/anorexia, abdominal pain, flatulence, and mild skin rash have been reported and probably are related to amiloride. Other adverse experiences that have been reported with amiloride are generally those known to be associated with diuresis, or with the underlying disease being treated.
The adverse reactions for MIDAMOR (amiloride) listed in the following table have been arranged into two groups: (1) incidence greater than one percent; and (2) incidence one percent or less. The incidence for group (1) was determined from clinical studies conducted in the United States (837 patients treated with MIDAMOR (amiloride) ). The adverse effects listed in group (2) include reports from the same clinical studies and voluntary reports since marketing. The probability of a causal relationship exists between MIDAMOR (amiloride) and these adverse reactions, some of which have been reported only rarely.
| Incidence >1% | Incidence ≤ 1% |
| Body as a Whole | |
|
Headache** Weakness Fatigability |
Back pain Chest pain Neck/shoulder ache Pain, extremities |
| Cardiovascular | |
| None |
Angina pectoris Orthostatic hypotension Arrhythmia Palpitation |
| Digestive | |
|
Nausea/anorexia** Diarrhea** Vomiting** Abdominal pain Gas pain Appetite changes Constipation |
Jaundice GI bleeding Abdominal fullness GI disturbance Thirst Heartburn Flatulence Dyspepsia |
| Metabolic | |
| Elevated serum potassium levels (> 5.5 mEq per Liter)*** | None |
| Skin | |
| None |
Skin rash Itching Dryness of mouth Pruritus Alopecia |
| Musculoskeletal | |
| Muscle cramps |
Joint pain Leg ache |
| Nervous | |
|
Dizziness Encephalopathy |
Paresthesia Tremors Vertigo |
| Psychiatric | |
| None |
Nervousness Mental confusion Insomnia Decreased libido Depression Somnolence |
| Respiratory | |
|
Cough Dyspnea | Shortness of breath |
| Special Senses | |
| None |
Visual disturbances Nasal congestion Tinnitus Increased intraocular pressure |
| Urogenital | |
| Impotence |
Polyuria Dysuria Urinary frequency Bladder spasms Gynecomastia |
** Reactions occurring in 3% to 8% of patients treated with MIDAMOR (amiloride) . (Those reactions occurring in less than 3% of the patients are unmarked.)
*** See BOXED WARNING.
Causal Relationship Unknown: Other reactions have been reported but occurred under circumstances where a causal relationship could not be established. However, in these rarely reported events, that possibility cannot be excluded. Therefore, these observations are listed to serve as alerting information to physicians.
- Activation of probable pre-existing peptic ulcer
- Aplastic anemia
- Neutropenia
- Abnormal liver function
Read the entire FDA prescribing information for Midamor (Amiloride) »
Additional Midamor Information
Midamor - User Reviews
Midamor User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Here is a collection of user reviews for the medication Midamor sorted by most helpful.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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