"Medscape Medical News
August 22, 2015
The US Food and Drug Administration (FDA) has granted tentative approval to expand the label for an extended-release formulation of topiramate (Trokendi XR, Supernus "...
(isometheptene mucate, dichloralphenazone and acetaminophen)
Each red capsule contains Isometheptene Mucate USP, 65 mg, Dichloralphenazone USP, 100 mg, and Acetaminophen USP, 325 mg.
Isometheptene Mucate is a white crystalline powder having a characteristic aromatic odor and bitter taste. It is an unsaturated aliphatic amine with sympathomimetic properties.
Acetaminophen, a non-salicylate, occurs as a white, odorless, crystalline powder, possessing a slightly bitter taste.
Midrin (acetaminophen, isometheptene and dichloralphenazone) capsules contain FD&C Yellow No. 6 as a color additive.
What are the possible side effects of acetaminophen, dichloralphenazone, and isometheptene (Epidrin, Midrin, Migquin, Migragesic IDA)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using the medicine and call your doctor at once if you have a serious side effect such as:
- low fever with nausea, stomach pain, and loss of appetite;
- dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- fast or uneven heart rate;
- easy bruising or bleeding, unusual weakness;...
What are the precautions when taking acetaminophen, isometheptene and dichloralphenazone (Midrin)?
See also Warning section.
Before taking this medication, tell your doctor or pharmacist if you are allergic to isometheptene, acetaminophen, or dichloralphenazone; or to chloral hydrate; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood circulation problems (for example, in your legs, arms/hands), high blood pressure, glaucoma, heart problems (such as chest pain, previous heart attack), kidney disease, liver disease, history of regular use/abuse of drugs/alcohol, stroke or "mini-stroke" (transient ischemic attack).
This drug may make you...
Last reviewed on RxList: 6/26/2008
This monograph has been modified to include the generic and brand name in many instances.
Additional Midrin Information
Midrin - User Reviews
Midrin User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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