In this Article

• What is acetaminophen, dichloralphenazone, and isometheptene (Midrin)?
• What are the possible side effects of acetaminophen, dichloralphenazone, and isometheptene?
• What is the most important information I should know about acetaminophen, dichloralphenazone, and isometheptene?
• What should I discuss with my healthcare provider before taking acetaminophen, dichloralphenazone, and isometheptene?
• How should I take acetaminophen, dichloralphenazone, and isometheptene?
• What happens if I miss a dose?
• What happens if I overdose?
• What should I avoid while taking acetaminophen, dichloralphenazone, and isometheptene?
• What other drugs will affect acetaminophen, dichloralphenazone, and isometheptene?
• Where can I get more information?

What happens if I miss a dose?

Since acetaminophen, dichloralphenazone, and isometheptene is taken only when needed, you will not be on a daily dosing schedule.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Other overdose symptoms may include severe dizziness or drowsiness, feeling restless or cold, changes in your breathing or heart rate, and fainting.

What should I avoid while taking acetaminophen, dichloralphenazone, and isometheptene?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. Alcohol can cause headaches, and may also increase your risk of liver damage while taking acetaminophen.

Do not use any cold, allergy, pain, migraine, or sleep medication without first asking your doctor or pharmacist. Acetaminophen (sometimes abbreviated as "APAP") is contained in many combination medicines. If you use certain products together you may accidentally use too much acetaminophen. Read the label of any other medicine you are using to see if it contains acetaminophen, or APAP.

What other drugs will affect acetaminophen, dichloralphenazone, and isometheptene?

Before using this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by acetaminophen, dichloralphenazone, and isometheptene.

Tell your doctor about all other medications you use, especially:

• a blood thinner such as warfarin (Coumadin);
• isoniazid (for treating tuberculosis); or
• an antidepressant such as amitriptyline (Elavil, Vanatrip), doxepin (Sinequan), desipramine (Norpramin), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), and others.

This list is not complete and there may be other drugs that can interact with acetaminophen, dichloralphenazone, and isometheptene. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about acetaminophen, dichloralphenazone, and isometheptene.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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