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Midrin

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Midrin

Midrin Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Midrin (isometheptene mucate, dichloralphenazone and acetaminophen) is used to treat migraine headaches or severe tension headaches. It is a combination of three drugs: acetaminophen, a pain reliever and fever reducer; dichloralphenazone, a sedative; and isometheptene, a vasoconstrictor. Midrin is no longer manufactured, but equivalents (medications that contain the same drug combination) may be available. Consult your doctor and pharmacist. Common side effects include dizziness, drowsiness, and nausea.

The usual adult dosage of Midrin is two capsules at once, followed by one capsule every hour until relieved, up to 5 capsules within a 12-hour period. Midrin or equivalent medications may interact with blood thinners, isoniazid, or antidepressants. Acetaminophen is contained in many combination medicines. Read all labels carefully so you don't take too much acetaminophen. Tell your doctor all medications you are taking. During pregnancy, this medication should be used only when prescribed. Discuss the risks and benefits with your doctor. This medication passes into breast milk. Consult your doctor before breast-feeding.

Our Midrin (isometheptene mucate, dichloralphenazone and acetaminophen) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Midrin in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using the medicine and call your doctor at once if you have a serious side effect such as:

  • low fever with nausea, stomach pain, and loss of appetite;
  • dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • fast or uneven heart rate;
  • easy bruising or bleeding, unusual weakness; or
  • fever, chills, sore throat, body aches, flu symptoms.

Less serious side effects may include:

  • dizziness, drowsiness;
  • mild nausea; or
  • mood changes.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Midrin (Acetaminophen, Isometheptene and Dichloralphenazone) »

What is Patient Information Overview?

A concise overview of the drug for the patient or caregiver from First DataBank.

Midrin Overview - Patient Information: Side Effects

SIDE EFFECTS: See also Warning section.

Dizziness, drowsiness, or nausea may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Read the entire patient information overview for Midrin (Acetaminophen, Isometheptene and Dichloralphenazone)»

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Midrin FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

Transient dizziness and skin rash may appear in hypersensitive patients. This can usually be eliminated by reducing the dose.

Read the entire FDA prescribing information for Midrin (Acetaminophen, Isometheptene and Dichloralphenazone) »

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Midrin - User Reviews

Midrin User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Midrin sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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