"Dec. 18, 2012 -- People who can't get their high blood pressure down with drugs may be helped by a new procedure that deactivates overactive nerves in the kidneys, a small study shows.
The procedure is already available in Europe and "...
(prazosin hydrochloride) For Oral Use
MINIPRESS® (prazosin hydrochloride), a quinazoline derivative, is the first of a new chemical class of antihypertensives. It is the hydrochloride salt of 1-(4-amino-6,7-dimethoxy- 2-quinazolinyl)-4-(2-furoyl) piperazine and its structural formula is:
Molecular formula C19H21N5O4.HCl
It is a white, crystalline substance, slightly soluble in water and isotonic saline, and has a molecular weight of 419.87. Each 1 mg capsule of MINIPRESS (prazosin hcl) for oral use contains drug equivalent to 1 mg free base.
Inert ingredients in the formulations are: hard gelatin capsules (which may contain Blue 1, Red 3, Red 28, Red 40, and other inert ingredients); magnesium stearate; sodium lauryl sulfate; starch; sucrose.
What are the possible side effects of prazosin (Minipress)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- fast or pounding heartbeats or fluttering in your chest;
- feeling like you might pass out;
- trouble breathing;
- swelling in your hands, ankles, or feet; or
- penis erection that is painful or lasts 4 hours or longer.
Less serious side effects may include:
- mild dizziness;
- weakness, tired...
What are the precautions when taking prazosin hcl (Minipress)?
Before taking prazosin, tell your doctor or pharmacist if you are allergic to it; or to other alpha blockers (such as doxazosin, terazosin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as low blood pressure), kidney disease, uncontrolled attacks of deep sleep (narcolepsy), prostate cancer.
This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Do not drive or participate...
Last reviewed on RxList: 8/4/2009
This monograph has been modified to include the generic and brand name in many instances.
Additional Minipress Information
Minipress - User Reviews
Minipress User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Get tips on handling your hypertension.