"Dec. 18, 2012 -- People who can't get their high blood pressure down with drugs may be helped by a new procedure that deactivates overactive nerves in the kidneys, a small study shows.
The procedure is already available in Europe and "...
Accidental ingestion of at least 50 mg of MINIPRESS (prazosin hcl) in a two year old child resulted in profound drowsiness and depressed reflexes. No decrease in blood pressure was noted. Recovery was uneventful.
Should overdosage lead to hypotension, support of the cardiovascular system is of first importance. Restoration of blood pressure and normalization of heart rate may be accomplished by keeping the patient in the supine position. If this measure is inadequate, shock should first be treated with volume expanders. If necessary, vasopressors should then be used. Renal function should be monitored and supported as needed. Laboratory data indicate MINIPRESS (prazosin hcl) is not dialysable because it is protein bound.
MINIPRESS (prazosin hcl) is contraindicated in patients with known sensitivity to quinazolines, prazosin, or any of the inert ingredients.
Last reviewed on RxList: 8/4/2009
This monograph has been modified to include the generic and brand name in many instances.
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