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Minipress

High blood pressure facts

  • High blood pressure (hypertension) is designated as either essential (primary) hypertension or secondary hypertension and is defined as a consistently elevated blood pressure exceeding 140/90 mm Hg.
  • High blood pressure is called "the silent killer" because it often causes no symptoms for many years, even decades, until it finally damages certain critical organs.
  • Poorly controlled high blood pressure ultimately can cause damage to blood vessels in the eye, thickening of the heart muscle and heart attacks, hardening of the arteries (arteriosclerosis), kidney failure, and strokes.
  • Most antihypertensive medications can be used alone or in combination. Some are used only in combination. Some are preferred over others in certain specific medical situations. And some are not to be used (contraindicated) in other situations.
  • Several classes of antihypertensive medications are available, including ACE i...

Minipress

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OVERDOSE

Accidental ingestion of at least 50 mg of MINIPRESS (prazosin hcl) in a two year old child resulted in profound drowsiness and depressed reflexes. No decrease in blood pressure was noted. Recovery was uneventful.

Should overdosage lead to hypotension, support of the cardiovascular system is of first importance. Restoration of blood pressure and normalization of heart rate may be accomplished by keeping the patient in the supine position. If this measure is inadequate, shock should first be treated with volume expanders. If necessary, vasopressors should then be used. Renal function should be monitored and supported as needed. Laboratory data indicate MINIPRESS (prazosin hcl) is not dialysable because it is protein bound.

CONTRAINDICATIONS

MINIPRESS (prazosin hcl) is contraindicated in patients with known sensitivity to quinazolines, prazosin, or any of the inert ingredients.

Last reviewed on RxList: 8/4/2009
This monograph has been modified to include the generic and brand name in many instances.

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