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Minocin Capsules

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Minocin Capsules

Minocin Capsules

Minocin Capsules Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Minocin Capsules (minocycline hydrochloride) is used to treat many different bacterial infections, such as urinary tract infections, severe acne, gonorrhea, tick fever, chlamydia, and others. Minocin is a tetracycline antibiotic. This medication is available in generic form. Common side effects include nausea, vomiting, diarrhea, lightheadedness, dizziness, unsteadiness, drowsiness, mouth sores, or cough.

The usual adult dosage of Minocin Capsules is 200 mg initially followed by 100 mg every 12 hours. Dose may differ depending on the condition for which this drug is prescribed. Minocin Capsules may interact adversely with certain retinoids, digoxin, penicillins, warfarin, and live bacterial vaccines. Some antibiotics may decrease the effectiveness of hormonal birth control such as the pill, ring or patch. Ask your doctor if you should use additional reliable birth control methods while using this antibiotic. This medication is not recommended for use during pregnancy because of possible harm to a fetus. Women of child-bearing age should use effective birth control while using this medication. Consult your doctor. This medication passes into breast milk in very small amounts. Consult your doctor before breast-feeding.

Our Minocin Capsules Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Minocin Capsules in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • stomach cramps, diarrhea that is watery or bloody;
  • flu symptoms, sores in your mouth and throat;
  • pale or yellowed skin, weakness, dark colored urine, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • fever, skin rash, bruising, severe tingling or numbness, muscle weakness,
  • upper stomach pain, loss of appetite, jaundice (yellowing of the skin or eyes);
  • chest pain, irregular heart rhythm, cough, wheezing, feeling short of breath;
  • confusion, vomiting, swelling, weight gain, urinating less than usual or not at all;
  • headache or pain behind your eyes, ringing in your ears, vision problems;
  • joint pain or swelling with fever, swollen glands, muscle aches, general ill feeling, unusual thoughts or behavior, and/or seizure (convulsions); or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious side effects may include:

  • dizziness, tired feeling, spinning sensation;
  • joint or muscle pain;
  • discoloration of you skin or nails;
  • mild nausea, mild diarrhea, upset stomach;
  • mild skin rash or itching;
  • swollen tongue, discoloration of your gums; or
  • vaginal itching or discharge.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Minocin Capsules (Minocycline) »

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Minocin Capsules FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

Due to oral minocycline's virtually complete absorption, side effects to the lower bowel, particularly diarrhea, have been infrequent. The following adverse reactions have been observed in patients receiving tetracyclines.

Body as a whole: Fever, and discoloration of secretions.

Gastrointestinal: Anorexia, nausea, vomiting, diarrhea, dyspepsia, stomatitis, glossitis, dysphagia, enamel hypoplasia, enterocolitis, pseudomembranous colitis, pancreatitis, inflammatory lesions (with monilial overgrowth) in the oral and anogenital regions. Instances of esophagitis and esophageal ulcerations have been reported in patients taking the tetracycline-class antibiotics in capsule and tablet form. Most of these patients took the medication immediately before going to bed. (See DOSAGE AND ADMINISTRATION.)

Genitourinary: Vulvovaginitis.

Hepatic toxicity: Hyperbilirubinemia, hepatic cholestasis, increases in liver enzymes, fatal hepatic failure, and jaundice. Hepatitis, including autoimmune hepatitis, and liver failure have been reported. (See PRECAUTIONS.)

Skin: Alopecia, erythema nodosum, hyperpigmentation of nails, pruritus, toxic epidermal necrolysis, and vasculitis. Maculopapular and erythematous rashes. Exfoliative dermatitis has been reported. Fixed drug eruptions have been reported. Lesions occurring on the glans penis have caused balanitis. Erythema multiforme and Stevens-Johnson syndrome have been reported. Photosensitivity is discussed above. (See WARNINGS.) Pigmentation of the skin and mucous membranes has been reported.

Respiratory: Cough, dyspnea, bronchospasm, exacerbation of asthma, and pneumonitis.

Renal toxicity: Interstitial nephritis. Elevations in BUN have been reported and are apparently dose related. (See WARNINGS.) Reversible acute renal failure has been reported.

Musculoskeletal: Arthralgia, arthritis, bone discoloration, myalgia, joint stiffness, and joint swelling.

Hypersensitivity reactions: Urticaria, angioneurotic edema, polyarthralgia, anaphylaxis/anaphylactoid reaction (including shock and fatalities), anaphylactoid purpura, myocarditis, pericarditis, exacerbation of systemic lupus erythematosus and pulmonary infiltrates with eosinophilia have been reported. A transient lupus-like syndrome and serum sickness-like reactions also have been reported.

Blood: Agranulocytosis, hemolytic anemia, thrombocytopenia, leukopenia, neutropenia, pancytopenia, and eosinophilia have been reported.

Central Nervous System: Convulsions, dizziness, hypesthesia, paresthesia, sedation, and vertigo. Bulging fontanels in infants and benign intracranial hypertension (pseudotumor cerebri) in adults have been reported. (See PRECAUTIONS - General.) Headache has also been reported.

Other: When given over prolonged periods, tetracyclines have been reported to produce brown-black microscopic discoloration of the thyroid gland. Cases of abnormalthyroid function have been reported.

Tooth discoloration in children less than 8 years of age (see WARNINGS) and also, in adults has been reported.

Oral cavity discoloration (including tongue, lip, and gum) have been reported.

Tinnitus and decreased hearing have been reported in patients on MINOCIN ® .

The following syndromes have been reported. In some cases involving these syndromes, death has been reported. As with other serious adverse reactions, if any of these syndromes are recognized, the drug should be discontinued immediately:

Hypersensitivity syndrome consisting of cutaneous reaction (such as rash or exfoliative dermatitis), eosinophilia, and one or more of the following: hepatitis, pneumonitis, nephritis, myocarditis, and pericarditis. Fever and lymphadenopathy may be present.

Lupus-like syndrome consisting of positive antinuclear antibody; arthralgia, arthritis, joint stiffness, or joint swelling; and one or more of the following: fever, myalgia, hepatitis, rash, and vasculitis.

Serum sickness-like syndrome consisting of fever; urticaria or rash; and arthralgia, arthritis, joint stiffness, or joint swelling. Eosinophilia may be present.

Read the entire FDA prescribing information for Minocin Capsules (Minocycline) »

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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