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Miochol-E Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 2/7/2016

Miochol-E (acetylcholine chloride intraocular solution) is a parasympathomimetic preparation used to obtain contraction of the iris of the eye in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy, and other anterior segment surgery where rapid contraction may be required. Common side effects of Miochol-E include corneal swelling, clouding, and decompensation; slow heart rate, low blood pressure, flushing (warmth, redness, or tingly feeling), breathing difficulties, and sweating.

Miochol-E is instilled into the anterior chamber of the eye (the space in the eye that is behind the cornea and in front of the iris) before or after securing one or more sutures. Miochol-E may interact with topical nonsteroidal anti-inflammatory drugs (NSAIDs). Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Miochol-E. Consult your doctor before breastfeeding.

Our Miochol-E (acetylcholine chloride intraocular solution) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Miochol-E FDA Prescribing Information: Side Effects
(Adverse Reactions)


Infrequent cases of corneal edema, corneal clouding, and corneal decompensation have been reported with the use of intraocular acetylcholine.

Adverse reactions have been reported rarely which are indicative of systemic absorption. These include bradycardia, hypotension, flushing, breathing difficulties and sweating.

Read the entire FDA prescribing information for Miochol-E (Acetylcholine Chloride Intraocular Solution)

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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