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Miostat Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 2/7/2016

Miostat (carbachol intraocular solution) is a cholinergic agent that reduces the pressure in the eye by increasing the amount of fluid that drains from the eye and is used to treat glaucoma by lowering the pressure inside the eye. Common side effects of Miostat include burning, stinging, or tearing eyes, eye irritation, decreased vision in poor light, headache, watering mouth, increased sweating, increased urination, nausea, vomiting, stomach cramps, diarrhea, dizziness, feeling faint, flushing (warmth, redness, or tingly feeling, especially in the face), and irregular heartbeat.

Miostat is usually used during surgery and a physician will determine the dose. Miostat may interact with other eye medications, especially nonsteroidal anti-inflammatory drugs (NSAIDs). Do not use other eye medications during treatment with Miostat ophthalmic unless your doctor tells you to do so. Tell your doctor all medications and supplements you use. During pregnancy, Miostat should be used only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Our Miostat (carbachol intraocular solution) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Miostat in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • vision problems, seeing "floaters" in your vision;
  • feeling like you might pass out;
  • fast or slow heartbeats;
  • wheezing, trouble breathing; or
  • severe burning, stinging, or eye irritation after using the eye drops;

Less serious side effects may include:

  • headache;
  • stomach cramps, vomiting;
  • diarrhea;
  • mild eye irritation; or
  • increased sweating or urination.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Miostat (Carbachol Intraocular Solution)

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Miostat FDA Prescribing Information: Side Effects
(Adverse Reactions)



Corneal clouding, persistent bullous keratopathy, retinal detachment and postoperative iritis following cataract extraction have been reported.


Side effects such as flushing, sweating, epigastric distress, abdominal cramps, tightness in urinary bladder, and headache have been reported with topical or systemic application of carbachol.

The following additional reactions have been identified during post-approval use of MIOSTAT (carbachol intraocular solution, USP) in clinical practice. Because they are reported voluntarily from a population of unknown size, estimates of frequency cannot be made. The reactions, which have been chosen for inclusion due to either their seriousness, frequency of reporting, possible causal connection to MIOSTAT, or a combination of these factors, include: corneal edema, drug effect prolonged (miosis), eye inflammation, eye pain, intraocular pressure increased, ocular hyperemia, vision blurred, visual impairment, and vomiting.

Read the entire FDA prescribing information for Miostat (Carbachol Intraocular Solution)

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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