Mirapex (Pramipexole) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 9, 2012

Mirapex

Parkinson's Disease: Eating Right »

Introduction to eating right with Parkinson's disease

While there is no special diet required for people with Parkinson's disease, eating a well-balanced, nutritious diet is extremely beneficial. With the proper diet, our bodies work more efficiently, we have more energy, and Parkinson's disease medications will work properly.

This article addresses the basics of good nutrition. Please consult your doctor or dietitian before making any dietary changes. A registered dietitian can provide in-depth nutrition education, tailor these general guidelines to meet your needs, and help you create and follow a personal meal plan.

The Basics of Eating Well

Eat a variety of foods from each food category. Ask your doctor if you should take a daily vitamin supplement.
Maintain your weight through a proper balance of exercise and food. Ask your doctor what your "goal" weight should be and how many calories you should consume ...

Read the Parkinson's Disease: Eating Right article »

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Mirapex User Reviews >>

Mirapex

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Mirapex®
(pramipexole dihydrochloride) 0.125 mg, 0.25 mg, 0.5 mg, 0.75 mg, 1 mg, and 1.5 mg Tablets

DRUG DESCRIPTION

MIRAPEX tablets contain pramipexole, a nonergot dopamine agonist. The chemical name of pramipexole dihydrochloride is (S)-2-amino-4,5,6,7-tetrahydro-6 (propylamino) benzothiazole dihydrochloride monohydrate. Its empirical formula is C₁₀H₁₇N₃S·2HCl·H₂O, and its molecular weight is 302.27.

The structural formula is:

Mirapex®
(pramipexole dihydrochloride) Structural Formula Illustration

Pramipexole dihydrochloride is a white to off-white powder substance. Melting occurs in the range of 296°C to 301°C, with decomposition. Pramipexole dihydrochloride is more than 20% soluble in water, about 8% in methanol, about 0.5% in ethanol, and practically insoluble in dichloromethane.

MIRAPEX tablets, for oral administration, contain 0.125 mg, 0.25 mg, 0.5 mg, 0.75 mg, 1 mg, or 1.5 mg of pramipexole dihydrochloride monohydrate. Inactive ingredients consist of mannitol, corn starch, colloidal silicon dioxide, povidone, and magnesium stearate.

What are the possible side effects of pramipexole (Mirapex)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking pramipexole and call your doctor at once if you have any of these serious side effects:

extreme drowsiness, falling asleep suddenly, even after feeling alert;
hallucinations;
fever, stiff muscles, confusion, sweating, fast or uneven heartbeats;
nausea, sweating, feeling light-headed, fainting; or
restless...

Read All Potential Side Effects and See Pictures of Mirapex »

What are the precautions when taking pramipexole (Mirapex)?

Before taking pramipexole, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure, heart problems (e.g., irregular heartbeat, heart failure), kidney problems, mental/mood disorders (e.g., confusion, hallucinations, psychosis, schizophrenia), sleep disorder (e.g., sleep apnea, narcolepsy).

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic...

Read All Potential Precautions of Mirapex »

Last reviewed on RxList: 6/20/2011
This monograph has been modified to include the generic and brand name in many instances.