Moduretic (Amiloride and Hydrochlorothiazide) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

Pill Identifier Search

May 26, 2012

« Previous
1
2
3
4
5
6
7
8
9
10
11
12
13
Next »

Moduretic User Reviews >>

Moduretic

High Blood Pressure (Hypertension) Slideshow

Take the Salt Quiz!

Lowering Blood Pressure Exercise Tips Pictures

font size

MODURETIC®
(amiloride HCl-hydrochlorothiazide)

DRUG DESCRIPTION

MODURETIC (Amiloride HCl-Hydrochlorothiazide) combines the potassium-conserving action of amiloride HCl with the natriuretic action of hydrochlorothiazide.

Amiloride HCl is designated chemically as 3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinecarboxamide monohydrochloride, dihydrate and has a molecular weight of 302.12. Its empirical formula is C₆H₈C_lN₇OH₀₂H₂O and its structural formula is:

Amiloride HCl structural formula illustration

Hydrochlorothiazide is designated chemically as 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide. Its empirical formula is C₇H₈C_lN₃O₄S₂ and its structural formula is:

Hydrochlorothiazide structural formula illustration

It is a white, or practically white, crystalline powder with a molecular weight of 297.74, which is slightly soluble in water, but freely soluble in sodium hydroxide solution.

MODURETIC (amiloride and hydrochlorothiazide) is available for oral use as tablets containing 5 mg of anhydrous amiloride HCl and 50 mg of hydrochlorothiazide. Each tablet contains the following inactive ingredients: calcium phosphate, FD&C Yellow 6, guar gum, lactose, magnesium stearate and starch.

What are the possible side effects of hydrochlorothiazide and amiloride (Moduretic 5-50)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have a serious side effect such as:

numbness or tingly feeling;
muscle pain or weakness;
slow, fast, or uneven heartbeat;
feeling drowsy, restless, or light-headed;
urinating less than usual or not at all;
dry mouth,...

Read All Potential Side Effects and See Pictures of Moduretic »

What are the precautions when taking amiloride and hydrochlorothiazide (Moduretic)?

See also Warning section.

Before taking this product, tell your doctor or pharmacist if you are allergic to amiloride or hydrochlorothiazide; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: untreated salt/mineral imbalance (such as high potassium, low sodium level), kidney disease, liver disease, diabetes, loss of too much body water (dehydration), lupus, gout, high levels of fats in the blood (cholesterol/triglycerides).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs,...

Read All Potential Precautions of Moduretic »

Last reviewed on RxList: 4/24/2009
This monograph has been modified to include the generic and brand name in many instances.