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In this Article

• What is hydrochlorothiazide and amiloride (Moduretic)?
• What are the possible side effects of hydrochlorothiazide and amiloride (Moduretic)?
• What is the most important information I should know about hydrochlorothiazide and amiloride (Moduretic)?
• What should I discuss with my doctor before taking hydrochlorothiazide and amiloride (Moduretic)?
• How should I take hydrochlorothiazide and amiloride (Moduretic)?
• What happens if I miss a dose (Moduretic)?
• What happens if I overdose (Moduretic)?
• What should I avoid while taking hydrochlorothiazide and amiloride (Moduretic)?
• What other drugs will affect hydrochlorothiazide and amiloride (Moduretic)?
• Where can I get more information?

What should I discuss with my doctor before taking hydrochlorothiazide and amiloride (Moduretic)?

Do not use this medication if you are allergic to hydrochlorothiazide or amiloride, or if you have:

• kidney disease or are unable to urinate;
• high potassium levels (hyperkalemia); or
• if you are taking potassium supplements.

Before using hydrochlorothiazide and amiloride, tell your doctor if you have:

• diabetes;
• heart disease;
• cirrhosis or other liver disease;
• a breathing disorder;
• gout;
• lupus;
• an allergy to sulfa drugs;
• a pancreas disorder; or
• if you are using another blood pressure medication or a steroid.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take hydrochlorothiazide and amiloride.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Hydrochlorothiazide passes into breast milk and could cause harm to a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take hydrochlorothiazide and amiloride (Moduretic)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take each dose with a full glass of water.

Take hydrochlorothiazide and amiloride with food.

While you are taking this medication, your blood pressure will need to be checked on a regular basis. Do not miss any scheduled appointments.

Your blood and urine may also be tested if you have been vomiting or are dehydrated.

Hydrochlorothiazide can interfere with the results of a thyroid test. Tell any doctor who treats you that you are using a thiazide diuretic.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking hydrochlorothiazide and amiloride. You may need to stop using the medicine for a short time.

If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.

Store the tablets at room temperature away from heat, light, and moisture. Do not allow the tablets to freeze.