- Do not concomitantly use disinfectants containing quaternary ammonium salts for skin preparation as hyaluronan can precipitate in their presence.
- Transient increases in inflammation in the injected knee following Monovisc™ injection have been reported in some patients with inflammatory osteoarthritis.
- Strict aseptic injection technique should be used during the application of Monovisc™.
- The safety and effectiveness of the use of Monovisc™ in joints other than the knee have not been demonstrated.
- The effectiveness of Monovisc™ has not been established for more than one course of treatment.
- STERILE CONTENTS. The pre-filled syringe is intended for single use only. The contents of the syringe should be used immediately after opening. Discard any unused Monovisc™. Do not resterilize.
- Do not use Monovisc™ if the package has been opened or damaged.
- Store Monovisc™ in its original package at room temperature (below 77°F/25°C). DO NOT FREEZE.
- Remove joint effusion, if present, before injecting Monovisc™.
- Only medical professionals trained in accepted injection techniques for delivering agents into the knee joint should inject Monovisc™ for the indicated use.
Information for Patients
- Transient pain or swelling may occur after the intra-articular (IA) injection.
- As with any invasive joint procedure, it is recommended that patients avoid strenuous or prolonged (i.e., more than one hour) weight-bearing activities such as running or tennis within 48 hours following the intra-articular injection.
Use In Specific Populations
The safety and effectiveness of the use of Monovisc™ in pregnant women has not been tested.
It is not known if Monovisc™ is excreted in human milk. The safety and effectiveness of the use of the product in lactating women has not been tested.
The safety and effectiveness of the use of Monovisc™ in pediatric patients ( ≤ 21 years of age) has not been tested.This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 3/21/2014
Additional Monovisc Information
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