Monurol (Fosfomycin) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 10, 2012

Monurol

Urinary Tract Infections in Children »

What is a urinary tract infection (UTI)?

A urinary tract infection is an infection of the bladder (cystitis) or kidney(s) (pyelonephritis). Cystitis is considerably more common than the more severe and more serious pyelonephritis.

What causes urinary tract infections in children?

Bacteria cause the large majority of urinary tract infections in children. Viral infection of the bladder is less common, while fungal infections of the urinary tract are rare and occur most commonly in immunocompromised individuals (for example, those with HIV/AIDS, chemotherapy recipients).

What are symptoms and signs of urinary tract infections (UTIs) in children?

Characteristic symptoms of a urinary tract infection include pain with urination (dysuria), urinary frequency (needing to urinate frequently) and urgency (feeling a compelling urge to urinate) and loss of previously established urinary control (for...

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MONUROL®
[mon'ur ol]
(fosfomycin tromethamine) Sachet

DRUG DESCRIPTION

MONUROL (fosfomycin tromethamine) sachet contains fosfomycin tromethamine, a synthetic, broad spectrum, bactericidal antibiotic for oral administration. It is available as a single-dose sachet which contains white granules consisting of 5.631 grams of fosfomycin tromethamine (equivalent to 3 grams of fosfomycin), and the following inactive ingredients: mandarin flavor, orange flavor, saccharin, and sucrose. The contents of the sachet must be dissolved in water. Fosfomycin tromethamine, a phosphonic acid derivative, is available as (1R,2S)-(1,2-epoxypropyl)phosphonic acid, compound with 213 amino-2-(hydroxymethyl)-1,3-propanediol (1:1). It is a white granular compound with a molecular weight of 259.2. Its empirical formula is C₃H₇O₄P.C₄H₁₁NO₃, and its chemical structure is as follows:

MONUROL (fosfomycin tromethamine) Structural Formula Illustration

What are the possible side effects of fosfomycin (Monurol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may be more likely to occur, such as:

diarrhea, nausea, stomach pain or upset;
headache;
dizziness;
weakness;
stuffy nose, sore throat;
menstrual pain;
back pain; or
vaginal itching or discharge.

Side effects other than those listed here may also...

Read All Potential Side Effects and See Pictures of Monurol »

What are the precautions when taking fosfomycin (Monurol)?

Before taking fosfomycin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as the artificial sweetener saccharin), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease.

Do not use more than a single dose (1 packet or sachet) of this medication for each bladder infection. Using more packets will not make the drug work any better and may increase side effects.

If you develop symptoms of a kidney infection (such as pain in side/lower back area, fever, chills), contact your doctor immediately. You may need a different...

Read All Potential Precautions of Monurol »

Last reviewed on RxList: 5/31/2011
This monograph has been modified to include the generic and brand name in many instances.