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Mozobil

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Mozobil

MOZOBIL
(plerixafor) Injection

DRUG DESCRIPTION

Mozobil (plerixafor injection) is a sterile, preservative-free, clear, colorless to pale yellow, isotonic solution for subcutaneous injection. Each mL of the sterile solution contains 20 mg of plerixafor. Each single-use vial is filled to deliver 1.2 mL of the sterile solution that contains 24 mg of plerixafor and 5.9 mg of sodium chloride in Water for Injection adjusted to a pH of 6.0 to 7.5 with hydrochloric acid and with sodium hydroxide, if required.

Plerixafor is a hematopoietic stem cell mobilizer with a chemical name l, 1'-[1,4phenylenebis (methylene)]-bis-1,4,8,11-tetraazacyclotetradecane. It has the molecular formula C28H54N8. The molecular weight of plerixafor is 502.79 g/mol. The structural formula is provided in Figure 1.

Figure 1: Structural Formula

MOZOBIL (plerixafor) Structural Formula Illustration

Plerixafor is a white to off-white crystalline solid. It is hygroscopic. Plerixafor has a typical melting point of 131.5 °C. The partition coefficient of plerixafor between 1octanol and pH 7 aqueous buffer is < 0.1.

What are the possible side effects of plerixafor (Mozobil)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have a serious side effect such as:

  • easy bruising or bleeding, unusual weakness;
  • feeling like you might pass out; or
  • pain in your upper stomach, spreading to your shoulder or back.

Less serious side effects may include:

  • nausea, vomiting;
  • diarrhea, constipation;
  • dry mouth, numbness in or around your mouth;
  • upset...

Read All Potential Side Effects and See Pictures of Mozobil »

Last reviewed on RxList: 6/20/2013
This monograph has been modified to include the generic and brand name in many instances.

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