Mozobil (Plerixafor Injection) Patient Information: How Should I Take the Drug at RxList

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May 27, 2012

Mozobil

Multiple Myeloma »

What is multiple myeloma?

Multiple myeloma is a type of cancer. Cancer is a group of many related diseases. Myeloma is a cancer that starts in plasma cells, a type of white blood cell. It's the most common type of plasma cell cancer.

Normal blood cells

Most blood cells develop from cells in the bone marrow called stem cells. Bone marrow is the soft material in the center of most bones.

Stem cells mature into different types of blood cells. Each type has a special job:

White blood cells help fight infection. There are several types of white blood cells.
Red blood cells carry oxygen to tissues throughout the body.
Platelets help form blood clots that control bleeding.

Plasma cells are white blood cells that make antibodies. Antibodies are part of the immune system. They work with other parts of the immune system to help protect the body from germs and other ...

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Mozobil

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Mozobil Patient Information including How Should I Take

What should I discuss with my health care provider before taking plerixafor (Mozobil)?

You should not receive this medication if you are allergic to plerixafor, or if you have leukemia.

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take plerixafor, tell your doctor if you have kidney disease.

FDA pregnancy category D. Plerixafor can cause harm to an unborn baby or cause birth defects. Before you receive plerixafor, tell your doctor if you are pregnant. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment.

It is not known whether plerixafor passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How is plerixafor given (Mozobil)?

Plerixafor is given as an injection under the skin. You will receive this injection in a hospital or clinic setting.

Before receiving plerixafor, you will be given a medication called a granulocyte (GRAN-yoo-loe-site) colony stimulating factor, also called G-CSF. Some examples of a G-CSF are filgrastim (Neupogen), pegfilgrastim (Neulasta), and sargramostim (Leukine).

A G-CSF will cause your bone marrow to produce stem cells and certain white blood cells called granulocytes, which help support your immune system.

Plerixafor works together with the G-CSF by causing stem cells and granulocytes produced in the bone marrow to circulate into your blood stream where they can be collected in blood drawn from your vein.

After your blood is drawn, it will be processed so that the needed stem cells and granulocytes can be separated from other unneeded parts of the blood. These stem cells and granulocytes will then be "transplanted" back into your vein through an IV injection.

To be sure plerixafor is not causing harmful effects, your blood will need to be tested often during your treatment.

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