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MRSA Infection (cont.)

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What is a "superbug"?

The term "superbug" is a nonspecific word that is used to describe any microorganism that is resistant to at least one or more commonly used antibiotics. Some authors restrict its use to microorganisms resistant to two or more antibiotics. Unfortunately, the term superbug is used in the medical and popular press to describe several different types of organisms which can lead readers to be confused about specific diseases and the infectious agents that cause them. The most common bacteria described as superbugs are the following:

  • MRSA (Staphylococcus aureus strains resistant to multiple antibiotics)

  • VRE (Enterococcus species resistant to vancomycin)

  • PRSP (Streptococcus pneumoniae strains resistant to penicillin)

  • ESBLs (Escherichia coli and other Gram-negative bacteria resistant to antibiotics such as cephalosporins and monobactams)

Emerging superbugs may include multiple drug-resistant Clostridium difficile, VRSA (vancomycin-resistant S. aureus), and NDM Escherichia coli (New Delhi metallo-beta-lactamase resistant E. coli).

Where are other MRSA information sources?

http://www.emedicinehealth.com/slideshow_mrsa_pictures/article_em.htm

http://www.cdc.gov/mrsa/index.html

http://www.pnas.org/cgi/content/full/99/11/7687

http://www.cdc.gov/ncidod/EID/vol11no06/04-0831.htm

http://www.kaisernetwork.org/daily_reports/rep_index.cfm?DR_ID=45809

http://www.cdc.gov/ncidod/dhqp/ar_multidrugFAQ.html

http://pubs.acs.org/doi/abs/10.1021/ja207142h

REFERENCES:

eMedicine.com. Staphylococcus aureus Infections, 2009.

eMedicine.com. Staphylococcus Infections, 2010.

Kallen, A.J., S. Bulens, A. Reingold, et al. "Health Care-Associated Invasive MRSA Infections, 2005-2008." JAMA 304 (2010): 641-648. U.S. Centers for Disease Control and Prevention. MRSA Infections, 2009

U.S. Department of Health & Human Services, National Institutes of Health. MRSA, 2008.

U.S. Department of Health & Human Services, National Institutes of Health. Genes Key to Staph Disease Severity, 2009.



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Source: MedicineNet.com
http://www.medicinenet.com/mrsa_infection/article.htm

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