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Medication Guide

(morphine sulfate controlled-release) Tablets.


  • A strong prescription pain medicine that contains an opioid (narcotic) that is used to treat moderate to severe around-the-clock pain.

Important information about MS CONTIN:

  • Get emergency help right away if you take too much MS CONTIN (overdose). MS CONTIN overdose can cause life-threatening breathing problems that can lead to death.
  • Never give anyone else your MS CONTIN. They could die from taking it. Store MS CONTIN away from children and in a safe place to prevent stealing or abuse. Selling or giving away MS CONTIN is against the law.

Do not take MS CONTIN if you have:

  • severe asthma, trouble breathing, or other lung problems.
  • a bowel blockage or have narrowing of the stomach or intestines.

Before taking MS CONTIN, tell your healthcare provider if you have a history of:

  • head injury, seizures
  • liver, kidney, thyroid problems
  • problems urinating
  • pancreas or gallbladder problems
  • abuse of street or prescription drugs, alcohol addiction, or mental health problems.

Tell your healthcare provider if you are:

  • pregnant or planning to become pregnant. MS CONTIN may harm your unborn baby.
  • breastfeeding. MS CONTIN passes into breast milk and may harm your baby.
  • taking prescription or over the counter medicines, vitamins, or herbal supplements.

When taking MS CONTIN:

  • Do not change your dose. Take MS CONTIN exactly as prescribed by your healthcare provider.
  • Take each dose at the same time every day. If you miss a dose, take MS CONTIN as soon as possible and then take your next dose 8 or 12 hours later as directed by your healthcare provider. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take more than 1 dose in 8 hours.
  • Swallow MS CONTIN whole. Do not cut, break, chew, crush, dissolve, or inject MS CONTIN.
  • Call your healthcare provider if the dose you are taking does not control your pain.
  • Do not stop taking MS CONTIN without talking to your healthcare provider.
  • After you stop taking MS CONTIN, flush any unused tablets down the toilet.

While taking MS CONTIN Do Not:

  • Drive or operate heavy machinery, until you know how MS CONTIN affects you. MS CONTIN can make you sleepy, dizzy, or lightheaded.
  • Drink alcohol or use prescription or over-the-counter medicines that contain alcohol.

The possible side effects of MS CONTIN are:

  • constipation, nausea, sleepiness, vomiting, tiredness, headache, dizziness, abdominal pain. Call your healthcare provider if you have any of these symptoms and they are severe.

Get emergency medical help if you have:

  • trouble breathing, shortness of breath, fast heartbeat, chest pain, swelling of your face, tongue or throat, extreme drowsiness, or you are feeling faint.

These are not all the possible side effects of MS CONTIN. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. For more information go to dailymed.nlm.nih.gov

Last reviewed on RxList: 7/23/2012
This monograph has been modified to include the generic and brand name in many instances.

MS-Contin - User Reviews

MS-Contin User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication MS-Contin sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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