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In this Article

• What is this drug (Myobloc)?
• What are the possible side effects of botulinum toxin type B (Myobloc)?
• What is the most important information I should know about botulinum toxin type B (Myobloc)?
• What should I discuss with my healthcare provider before I receive botulinum toxin type B (Myobloc)?
• How is botulinum toxin type B given (Myobloc)?
• What happens if I miss a dose (Myobloc)?
• What happens if I overdose (Myobloc)?
• What should I avoid after receiving botulinum toxin type B (Myobloc)?
• What other drugs will affect botulinum toxin type B (Myobloc)?
• Where can I get more information?

What should I discuss with my healthcare provider before I receive botulinum toxin type B (Myobloc)?

You should not receive this medication if you are allergic to botulinum toxin.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely receive this medication:

• amyotrophic lateral sclerosis (ALS, or "Lou Gehrig's disease");
• myasthenia gravis; or
• Lambert-Eaton syndrome.

Botulinum toxin type B is made using human plasma (part of the blood) and may contain viruses and other infectious agents that can cause disease. Although donated human plasma is screened, tested, and treated to reduce the risk of it containing anything that could cause disease, there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.

FDA pregnancy category C. It is not know whether botulinum toxin is harmful to an unborn baby. Before you receive this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether botulinum toxin passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How is botulinum toxin type B given (Myobloc)?

Botulinum toxin type B is given as an injection into a muscle. A doctor, nurse, or other healthcare provider will give you this injection.

It may take up about 4 weeks after injection before neck muscle spasm symptoms begin to improve.

The effects of a botulinum toxin injection are temporary. Your symptoms may return completely within 3 months after an injection. After repeat injections, it may take less and less time before your symptoms return, especially if your body develops antibodies to the botulinum toxin.

Do not seek botulinum toxin injections from more than one medical professional at a time. If you switch healthcare providers, be sure to tell your new provider how long it has been since your last botulinum toxin injection.

Using this medication more often than prescribed will not make it more effective and may result in serious side effects.