"Over the course of 6 months, a single injection of 200 units of onabotulinumtoxinA resulted in a small but statistically significant greater reduction in daily episodes of urgency urinary incontinence than sacral neuromodulation, according to a r"...
Mirabegron has been administered to healthy volunteers at single doses up to 400 mg. At this dose, adverse events reported included palpitations (1 of 6 subjects) and increased pulse rate exceeding 100 bpm (3 of 6 subjects). Multiple doses of mirabegron up to 300 mg daily for 10 days showed increases in pulse rate and systolic blood pressure when administered to healthy volunteers. Treatment for overdosage should be symptomatic and supportive. In the event of overdosage, pulse rate, blood pressure and ECG monitoring is recommended.
MYRBETRIQ® is contraindicated in patients who have known hypersensitivity reactions to mirabegron or any component of the tablet [see ADVERSE REACTIONS].This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 8/29/2016
Additional Myrbetriq Information
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