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Side Effects


The most frequently occurring early side effects are ataxia and vertigo. These tend to disappear with continued therapy, or with reduction of initial dosage. Occasionally, the following have been reported: nausea, anorexia, vomiting, fatigue, hyperirritability, emotional disturbances, sexual impotency, diplopia, nystagmus, drowsiness, and morbilliform skin eruptions. Granulocytopenia, agranulocytosis, and red-cell hypoplasia and aplasia, have been reported rarely. These and, occasionally, other persistant or severe side effects may necessitate withdrawal of the drug. Megaloblastic anemia may occur as a rare idiosyncrasy to Mysoline (primidone) and to other anticonvulsants. The anemia responds to folic acid without necessity of discontinuing medication.

Read the Mysoline (primidone) Side Effects Center for a complete guide to possible side effects


No information provided.

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 8/12/2010

Side Effects

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