July 27, 2016
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Nafcillin Injection

Nafcillin Injection Patient Information including How Should I Take

What should I discuss with my healthcare provider before using nafcillin (Nafcillin Injection)?

You should not use this medication if you are allergic to nafcillin or to any other penicillin antibiotic, such as:

  • amoxicillin (Amoxil, Amoxicot, Biomox, Dispermox, Trimox);
  • ampicillin (Omnipen, Principen);
  • carbenicillin (Geocillin);
  • cloxacillin (Cloxapen);
  • dicloxacillin (Dycill, Dynapen);
  • oxacillin (Bactocill); or
  • penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids, and others).

Before using nafcillin, tell your doctor if you are allergic to any drugs (especially cephalosporins such as Ceftin, Cefzil, Keflex, Omnicef, and others), or if you have:

  • asthma;
  • liver disease;
  • kidney disease; or
  • a history of any type of allergy.

If you have any of these conditions, you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Nafcillin can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use nafcillin (Nafcillin Injection)?

Nafcillin is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.

Nafcillin is usually given every 4 hours. The medicine must be given slowly through an IV infusion, and can take up to 1 hour to complete.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when the medicine is injected.

To be sure this medicine is helping your condition, your blood will need to be tested often. Your liver and kidney function may also need to be tested. Visit your doctor regularly.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Nafcillin is usually given for up to 2 days after lab tests show that the infection has cleared.

Nafcillin in vials (bottles) should be stored at room temperature away from moisture and heat.

Nafcillin that is supplied in a premixed frozen solution should be stored in a deep freezer at a temperature of 4 degrees below 0.

Thaw the medicine either in a refrigerator or at room temperature. Do not heat the medicine to thaw it more quickly.

Nafcillin that is thawed in the refrigerator should be used within 21 days. If you have thawed the medicine at room temperature, you must use it within 72 hours. Do not refreeze.

Once nafcillin has been thawed, it should look clear. Do not use the medicine if it looks cloudy or has particles in it, or if the medicine container leaks. Call your doctor or pharmacist for a new prescription

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